Projects funded by the NCN

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69 projects found matching your search criteria :

  1. Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi...

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Joanna Mika

    Instytut Farmakologii PAN

  2. The influence of molecular fingerprint bit density on chemical pattern recognition effectiveness

    Call: PRELUDIUM 2 , Panel: NZ2

    Principal investigator: Rafał Kurczab

    Instytut Farmakologii PAN

  3. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application...

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Sabina Podlewska

    Instytut Farmakologii PAN

  4. Neuronal and nonneuronal mechanisms of Bont/A effects in neuropathic pain development - behavioral and biochemical studi...

    Call: HARMONIA 5 , Panel: NZ4

    Principal investigator: dr hab. Joanna Mika

    Instytut Farmakologii PAN

  5. The significance of the serotonergic innervation of the brain hypothalamus in the regulation of cytochrome P450

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Władysława Daniel

    Instytut Farmakologii PAN

  6. Neurotoxic effects of benzophenone-3 : the role of estrogen receptors and retinoid X receptor alpha.

    Call: PRELUDIUM 7 , Panel: NZ4

    Principal investigator: Agnieszka Wnuk

    Instytut Farmakologii PAN

  7. Examine the importance of intracellular pathways in the action of opioids in microglial cells in vitro

    Call: PRELUDIUM 4 , Panel: NZ3

    Principal investigator: Katarzyna Popiołek-Barczyk

    Instytut Farmakologii PAN

  8. The effects of positive allosteric modulators of alpha7 nicotinic acetylcholine receptors on complex cognitive processes...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Nikiforuk

    Instytut Farmakologii PAN

  9. Effects of prenatal stress on properities of neurons and synaptic transmission in dorsal raphe nucleus of the rat

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Joanna Sowa

    Instytut Farmakologii PAN

  10. seQinspector - genome-wide analysis of gene transcription regulation mechanisms

    Call: PRELUDIUM 1 , Panel: NZ2

    Principal investigator: dr Marcin Piechota

    Instytut Farmakologii PAN

  11. Neurobiological basis of sensation seeking behaviour

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Magdalena Sikora

    Instytut Farmakologii PAN

  12. The study of the role of mGluR8 in cancer cells - a potential target for new antitumor strategies

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Danuta Jantas

    Instytut Farmakologii PAN

  13. Effects of restraint stress on properties of neurons and synaptic transmission in hypothalamic paraventricular nucleus o...

    Call: PRELUDIUM 4 , Panel: NZ4

    Principal investigator: Magdalena Kusek

    Instytut Farmakologii PAN

  14. Neural mechanisms underlying pathology of motivation.

    Call: SONATA BIS 2 , Panel: NZ3

    Principal investigator: dr Jan Rodriguez-Parkitna

    Instytut Farmakologii PAN

  15. Research on influence of antidepressant drugs on serum and brain levels of neurotrophins in rats, affected by the time d...

    Call: OPUS 4 , Panel: NZ4

    Principal investigator: dr Maciej Kuśmider

    Instytut Farmakologii PAN

  16. "Legal Higsh"- CNS effects and neurotoxicity

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Krystyna Gołembiowska

    Instytut Farmakologii PAN

  17. Identification of cytochrome P450 isoenzymes involved in the metabolism of levomepromazine in the human

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Jacek Wójcikowski

    Instytut Farmakologii PAN

  18. Neuroplasticity regulation by alternative gene transcription

    Call: SONATA 2 , Panel: NZ3

    Principal investigator: dr Michał Korostyński

    Instytut Farmakologii PAN

  19. The molecular basis of stress-induced anxiety and affective disorders

    Call: OPUS 2 , Panel: NZ2

    Principal investigator: dr Michał Korostyński

    Instytut Farmakologii PAN

  20. The effects of ligands of the alpha7 nicotinic acetylcholine receptors on complex cognitive processes and social behavio...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Agnieszka Potasiewicz

    Instytut Farmakologii PAN

  21. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

    Call: HARMONIA 7 , Panel: NZ2

    Principal investigator: Stefan Mordalski

    Instytut Farmakologii PAN

  22. Antidepressats as substances that increase the activity of risperidone, an atypical antipsychotic drug in animal models

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Katarzyna Kamińska

    Instytut Farmakologii PAN

  23. Evaluation of histopathological changes in the rats tissues after acute and chronic administration of the compounds from...

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Edyta Możdżeń

    Instytut Farmakologii PAN

  24. Noradrenergic modulation of cocaine-seeking

    Call: SONATA 6 , Panel: NZ4

    Principal investigator: dr Wojciech Solecki

    Instytut Farmakologii PAN

  25. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii PAN

  26. Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  27. Unusual 5-HT6 receptor ligands

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Andrzej Bojarski

    Instytut Farmakologii PAN

  28. The group III metabotropic glutamate receptors as a target for future antypsychotic drugs

    Call: MAESTRO 3 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii PAN

  29. PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

    Call: SONATA BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Starowicz-Bubak

    Instytut Farmakologii PAN

  30. Molecular markers of stress resilience in animal model of depression

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Marta Dziedzicka-Wasylewska

    Instytut Farmakologii PAN

  31. The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: Jan Detka

    Instytut Farmakologii PAN

  32. Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr Jan Rodriguez Parkitna

    Instytut Farmakologii PAN

  33. Glucocorticoid-induced alterations of astrocytic metabolism in stress-related disorders.

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: dr Michał Ślęzak

    Instytut Farmakologii PAN

  34. The role of microRNA biogenesis system in vulnerability and resilience to stress in an animal model of depression

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Dariusz Żurawek

    Instytut Farmakologii PAN

  35. Contribution of nitrergic transmission in the modulation of L-dopa activity in the rat 6-OHDA model of Parkinson's disea...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Elżbieta Lorenc-Koci

    Instytut Farmakologii PAN

  36. Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodege...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  37. The role of glucocorticoids in the regulaton of neurodegenerative prosses

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Anna Kurek

    Instytut Farmakologii PAN

  38. The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr Joanna Solich

    Instytut Farmakologii PAN

  39. Effect of paroxetine and risperidone on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptor in the conte...

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: dr Magdalena Kolasa

    Instytut Farmakologii PAN

  40. Plasticity of glutamatergic synapses on dopamine neurons: the mechanism of habit formation.

    Call: HARMONIA 3 , Panel: NZ4

    Principal investigator: dr hab. Jan Rodriguez-Parkitna

    Instytut Farmakologii PAN

  41. Activation of endogenous pronociceptive mechanisms of opioid system as an important factors in the development of neurop...

    Call: MAESTRO 3 , Panel: NZ4

    Principal investigator: prof. Barbara Przewłocka

    Instytut Farmakologii PAN

  42. Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

    Call: HARMONIA 4 , Panel: NZ7

    Principal investigator: dr Bernadeta Szewczyk

    Instytut Farmakologii PAN

  43. Molecular mechanism for the effects of stress hormones on development of drug addiction

    Call: MAESTRO 4 , Panel: NZ3

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii PAN

  44. Transcription factor MeCP2 as an intracellular object of study on the mechanism of depression and as a potential pharmac...

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Magdalena Sowa-Kućma

    Instytut Farmakologii PAN

  45. The effect of imipramine and risperidone on regulation of the chronic mild stress-induced anhedonia and memory impairmen...

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: dr hab. Mariusz Papp

    Instytut Farmakologii PAN

  46. Pessimism as cognitive biomarker of depression in animal model

    Call: OPUS 7 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii PAN

  47. Molecular mechanism of action of antidepressant drugs in the in vitro model of contact allergy in the human cell line Ha...

    Call: PRELUDIUM 7 , Panel: NZ6

    Principal investigator: Katarzyna Curzytek

    Instytut Farmakologii PAN

  48. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

    Call: SONATA 8 , Panel: NZ7

    Principal investigator: dr Rafał Kurczab

    Instytut Farmakologii PAN

  49. Molecular mechanism of unique action of clozapine in the context of GPCR.

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr Agata Faron-Górecka

    Instytut Farmakologii PAN

  50. The impact of early-life stress (maternal separation) and fluctuation in corticosterone levels during adolescence on pre...

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Iwona Majcher-Maślanka

    Instytut Farmakologii PAN

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