Projects funded by the NCN

New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Agnieszka Wnuk

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: dr Ewa Izabela Trojan

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto...

Call: OPUS 9 , Panel: NZ4

Principal investigator: dr Magdalena Joanna Zaniewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Wpływ wybranych chemokin na właściwości komórek nerwowych i przekaźnictwo synaptyczne w obszarze kompleksu ciała migdało...

Call: ETIUDA 7 , Panel: NZ4

Principal investigator: Joanna Ewa Sowa

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The study of the role of mGluR8 in cancer cells - a potential target for new antitumor strategies

Call: OPUS 3 , Panel: NZ3

Principal investigator: dr Danuta Jantas

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The group III metabotropic glutamate receptors as a target for future antypsychotic drugs

Call: MAESTRO 3 , Panel: NZ7

Principal investigator: prof. Andrzej Pilc

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

"Epigenetic mechanisms underlying cocaine seeking and relapse"

Call: MAESTRO 3 , Panel: NZ3

Principal investigator: prof. Małgorzata Maria Filip

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

Call: SONATA BIS 2 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Neurobiology of optimism; Characterisation of the neuroanatomical and neurochemical substrates of cognitive judgement bi...

Call: SONATA BIS 2 , Panel: NZ4

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The research of molecular markers for neuroprotective effect of tetrahydroisoquinolines based on various eksperimental m...

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr Agnieszka Wąsik

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The effects of positive allosteric modulators of alpha7 nicotinic acetylcholine receptors on complex cognitive processes...

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Anna Nikiforuk

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The effect of imipramine and risperidone on regulation of the chronic mild stress-induced anhedonia and memory impairmen...

Call: OPUS 5 , Panel: NZ7

Principal investigator: Mariusz Papp

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Motor thalamic nuclei as a potential therapeutic target for adenosine in parkinsonian and essential tremor; behavioural,...

Call: OPUS 6 , Panel: NZ4

Principal investigator: dr hab. Jadwiga Wardas

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The effect of the novel atypical neuroleptics on the activity and expression of cytochrome P450 isoforms in human liver

Call: OPUS 6 , Panel: NZ7

Principal investigator: dr hab. Jacek Wójcikowski

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

Call: OPUS 7 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

Call: OPUS 7 , Panel: NZ7

Principal investigator: dr Grzegorz Kreiner

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The impact of maternal diabetes on inflammasome NLRP3 activation in the offspring brain

Call: PRELUDIUM 7 , Panel: NZ7

Principal investigator: dr Katarzyna Elżbieta Głombik

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The effect of social stress during adolescence on the psychotic symptoms development and epigenetic mechanisms in the ne...

Call: OPUS 7 , Panel: NZ4

Principal investigator: dr hab. Marzena Małgorzata Maćkowiak

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Fluorine substitution – a new algorithm for increasing biological activity

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Wojciech Pietruś

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Katarzyna Elżbieta Głombik

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The effect of omega-3 fatty acid-enriched diet on the myelination impairment and the depression-like phenotype induced b...

Call: SONATA 16 , Panel: NZ5

Principal investigator: dr Irena Maria Smaga-Maślanka

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Novel hope for diseased joints: a polymer-based treatment to promoteregenerative strategies for patients with osteoarthr...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Marta Kędziora

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: dr Magdalena Białoń

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

Call: OPUS 23 , Panel: NZ7

Principal investigator: dr Katarzyna Anna Szczepańska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Early-life programming for neurodevelopmental disorders: search for a prodrome target within the vascular network in a r...

Call: OPUS 23 , Panel: NZ4

Principal investigator: prof. Małgorzata Maria Filip

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

"I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Agnieszka Wnuk

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Modeling Progression of α-Synucleinopathy in Noradrenergic and Serotonergic Systems – Possible Link with Prodromal Sympt...

Call: PRELUDIUM 23 , Panel: NZ4

Principal investigator: Anna Hajam Alwani

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation...

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Agata Faron-Górecka

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Effects of ketamine optical isomers on motivation and decision-making in rats using deep learning for behavioral analysi...

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Natalia Alicja Malikowska-Racia

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Modulation of 5-HT7 receptor signaling as common mechanism involved in the long-lasting antidepressant effects of typica...

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Barbara Wanda Chruścicka-Smaga

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Reinforcement sensitivity phenotypes as determinants of various motivational styles of alcohol drinking: craving for rew...

Call: OPUS 28 , Panel: HS6

Principal investigator: prof. Rafał Ryguła

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of selected signaling pathways in zinc deficiency

Call: OPUS 10 , Panel: NZ4

Principal investigator: prof. Gabriel Piotr Nowak

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Neurodevelopmental patomechanisms of triclocarban- and dichlorodiphenyldichloroetylene-induced effects: the role of apop...

Call: OPUS 10 , Panel: NZ7

Principal investigator: dr hab. Małgorzata Kajta

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Molecular characteristics of stress-resilient phenotype using mice models.

Call: OPUS 12 , Panel: NZ4

Principal investigator: prof. Marta Dziedzicka-Wasylewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context...

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr Grzegorz Kreiner

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

Call: PRELUDIUM 13 , Panel: NZ5

Principal investigator: dr Anna Maria Rafało-Ulińska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Contribution of nitrergic transmission in the modulation of L-dopa activity in the rat 6-OHDA model of Parkinson's disea...

Call: OPUS 1 , Panel: NZ4

Principal investigator: dr hab. Elżbieta Kazimiera Lorenc-Koci

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr Jan Manuel Rodriguez Parkitna

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Modified maternal diet as a factor of autism spectrum disorders in offspring - preclinical molecular studies on prefront...

Call: PRELUDIUM 15 , Panel: NZ7

Principal investigator: Kinga Eryka Gawlińska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec...

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of nitric oxide-dependent pathways in the procognitive effects of muscarinic and metabotropic glutamate recepto...

Call: OPUS 17 , Panel: NZ7

Principal investigator: dr hab. Joanna Monika Wierońska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Znaczenie interakcji układu endokanabinoidowego i endowaniloidowego w leczeniu bólu przewlekłego - potencjał terapeutycz...

Call: ETIUDA 3 , Panel: NZ7

Principal investigator: Natalia Eleonora Małek

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Altered interaction between NMDA receptor subunits and their scaffolding proteins as a critical step to control drug see...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Małgorzata Maria Filip

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Simultaneous stimulation of muscarinic M4 receptor and selected receptors involved in the regulation of glutamate releas...

Call: OPUS 9 , Panel: NZ7

Principal investigator: dr hab. Joanna Monika Wierońska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi...

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr hab. Joanna Gabriela Mika

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodege...

Call: OPUS 2 , Panel: NZ7

Principal investigator: dr Grzegorz Kreiner

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of glucocorticoids in the regulaton of neurodegenerative prosses

Call: PRELUDIUM 3 , Panel: NZ7

Principal investigator: Anna Jadwiga Kurek

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat...

Call: OPUS 3 , Panel: NZ4

Principal investigator: dr Joanna Solich

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Effect of paroxetine and risperidone on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptor in the conte...

Call: PRELUDIUM 3 , Panel: NZ7

Principal investigator: dr Magdalena Anna Kolasa

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk