Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Assessment of SARS-CoV-2 infection in patients with chronic lymphocytic leukemia depending on indicators of immune disorders, with particular emphasis on the role of interferons as natural compounds with therapeutic potential

2021/41/B/NZ6/01765

Keywords:

interferons chronic lymphocytic leukemia anti-coronavirus disease 2019 (COVID-19) vaccine Epstein-Barr virus (EBV) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) secondary immunodeficiency zebrafish interferonopathies

Descriptors:

  • NZ6_001:
  • NZ6_002:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Medyczny w Lublinie

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Ewelina Pia Grywalska 

Number of co-investigators in the project: 7

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 1 999 647 PLN

Project start date (Y-m-d): 2022-02-01

Project end date (Y-m-d): 2026-01-31

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  1. Immune Checkpoint Pathway Expression in Lymphocyte Subpopulations in Patients with Common Variable Immunodeficiency and Chronic Lymphocytic Leukemia
    Authors:
    Paulina Mertowska, Sebastian Mertowski, Konrad Smolak, Aleksandra Kita, Gabriela Kita, Katarzyna Guz, Marcin Pasiarski, Ewelina Grywalska
    Academic press:
    Cancers (rok: 2023, tom: 15, strony: 17), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers15215184 - link to the publication
  2. Unraveling the Role of Toll-like Receptors in the Immunopathogenesis of Selected Primary and Secondary Immunodeficiencies
    Authors:
    Paulina Mertowska, Konrad Smolak, Sebastian Mertowski, Ewelina Grywalska
    Academic press:
    Cells (rok: 2023, tom: 12, strony: 45684), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12162055 - link to the publication
  3. Immunomodulatory Role of Interferons in Viral and Bacterial Infections
    Authors:
    Paulina Mertowska, Konrad Smolak, Sebastian Mertowski, Ewelina Grywalska
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24, strony: 45688), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms241210115 - link to the publication
  4. Programmed Cell Death-1/Programmed Cell Death-1 Ligand as Prognostic Markers of Coronavirus Disease 2019 Severity
    Authors:
    Paulina Niedźwiedzka-Rystwej, Adam Majchrzak, Bogusz Aksak-Wąs, Karol Serwin, Zenon Czajkowski, Ewelina Grywalska, Izabela Korona-Głowniak, Jacek Roliński, Miłosz Parczewski
    Academic press:
    Cells (rok: 2022, tom: 11, strony: 45672), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells11121978 - link to the publication
  5. SARS-CoV-2 Seroprevalence in HealthcareWorkers before the Vaccination in Poland: Evolution from the First to the Second Pandemic Outbreak
    Authors:
    Izabela Korona-Głowniak, Michał Mielnik, Martyna Podgajna, Ewelina Grywalska, Marek Hus, Katarzyna Matuska, Beata Wojtysiak-Duma, Dariusz Duma, Andrzej Glowniak, Anna Malm
    Academic press:
    International Journal of Environmental Research and Public Health (rok: 2022, tom: 19, strony: 45670), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijerph19042319 - link to the publication
  6. Unraveling the Role of Toll-like Receptors in the Immunopathogenesis of Selected Primary and Secondary Immunodeficiencies
    Authors:
    Paulina Mertowska, Konrad Smolak, Sebastian Mertowski, Ewelina Grywalska
    Academic press:
    Cells (rok: 2023, tom: 12, strony: 45684), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12162055 - link to the publication
  7. Could Immune Checkpoint Disorders and EBV Reactivation Be Connected in the Development of Hematological Malignancies in Immunodeficient Patients?
    Authors:
    Paulina Mertowska, Sebastian Mertowski, Konrad Smolak, Gabriela Kita, Katarzyna Guz, Aleksandra Kita, Marcin Pasiarski, Jolanta Smok-Kalwat, Stanisław Góźdź, Ewelina Grywalska
    Academic press:
    Cancers (rok: 2023, tom: 15, strony: 45688), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers15194786 - link to the publication

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