LCRPlatform: new algorithms and methods for the comprehensive identification, categorization, and annotation of protein low complexity regions

2020/39/B/ST6/03447

Keywords

Descriptors

  • NZ2_007: Bioinformatyka
  • ST6_013: Bioinformatyka, bioobliczenia, obliczenia DNA i molekularne

Panel

ST6 – Computer science and informatics: informatics and information systems, computer science, scientific computing, intelligent systems

Host institution

Instytut Biochemii i Biofizyki PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Marcin Maciej Grynberg

Number of co-investigators in the project: 6

Call

OPUS 20 – announced on 2020-09-15

Amount awarded
1 004 670 PLN
Project start date
2021-09-30
Project end date
2026-09-29
Project duration
60 months (the same as in the proposal)
Project status
Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Insights from analyses of low complexity regions with canonical methods for protein sequence comparison

    Authors:
    Patryk Jarnot, Joanna Ziemska-Legiecka, Marcin Grynberg, Aleksandra Gruca
    Academic press:
    Briefings in Bioinformatics (year: 2022, volume: 23(5), pages: bbac299), Publisher: Oxford Academic Press
    Status:
    Published
    DOI:
    10.1093/bib/bbac299 – link to the publication
  2. The Cu(II) affinity constant and reactivity of Hepcidin-25, the main iron regulator in human blood

    Authors:
    Dawid Płonka, Marta D. Wiśniewska, Joanna Ziemska-Legięcka, Marcin Grynberg, Wojciech Bal
    Academic press:
    Journal of Inorganic Biochemistry (year: 2023, volume: 248, pages: 112364), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jinorgbio.2023.112364 – link to the publication
  3. LCRAnnotationsDB: a database of low complexity regions functional and structural annotations

    Authors:
    Joanna Ziemska-Legiecka, Patryk Jarnot, Sylwia Szymańska, Dagmara Błaszczyk, Alicja Staśczak, Hanna Langer-Macioł, Kinga Lucińska, Karolina Widzisz, Aleksandra Janas, Hanna Słowik, Wiktoria Śliwińska, Aleksandra Gruca & Marcin Grynberg
    Academic press:
    BMC Genomics (year: 2024, volume: 25, pages: 1251), Publisher: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12864-024-10960-5 – link to the publication

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Graphic design and implementation: Jakub Piotrowski