Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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LCRPlatform: new algorithms and methods for the comprehensive identification, categorization, and annotation of protein low complexity regions

2020/39/B/ST6/03447

Keywords:

protein low complexity regions algorithms comparison alignment annotation function

Descriptors:

  • NZ2_007:
  • ST6_013:

Panel:

ST6 - Computer science and informatics: informatics and information systems, computer science, scientific computing, intelligent systems

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marcin Maciej Grynberg 

Number of co-investigators in the project: 6

Call: OPUS 20 - announced on 2020-09-15

Amount awarded: 1 004 670 PLN

Project start date (Y-m-d): 2021-09-30

Project end date (Y-m-d): 2025-09-29

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Insights from analyses of low complexity regions with canonical methods for protein sequence comparison
    Authors:
    Patryk Jarnot, Joanna Ziemska-Legiecka, Marcin Grynberg, Aleksandra Gruca
    Academic press:
    Briefings in Bioinformatics (rok: 2022, tom: 23(5), strony: bbac299), Wydawca: Oxford Academic Press
    Status:
    Published
    DOI:
    10.1093/bib/bbac299 - link to the publication
  2. LCRAnnotationsDB: a database of low complexity regions functional and structural annotations
    Authors:
    Joanna Ziemska-Legiecka, Patryk Jarnot, Sylwia Szymańska, Dagmara Błaszczyk, Alicja Staśczak, Hanna Langer-Macioł, Kinga Lucińska, Karolina Widzisz, Aleksandra Janas, Hanna Słowik, Wiktoria Śliwińska, Aleksandra Gruca & Marcin Grynberg
    Academic press:
    BMC Genomics (rok: 2024, tom: 25, strony: 1251), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12864-024-10960-5 - link to the publication
  3. The Cu(II) affinity constant and reactivity of Hepcidin-25, the main iron regulator in human blood
    Authors:
    Dawid Płonka, Marta D. Wiśniewska, Joanna Ziemska-Legięcka, Marcin Grynberg, Wojciech Bal
    Academic press:
    Journal of Inorganic Biochemistry (rok: 2023, tom: 248, strony: 112364), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jinorgbio.2023.112364 - link to the publication