Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Regulatory mechanism involved in riboflavin overproduction in the flavinogenic yeast Candida famata

2018/29/B/NZ1/01497

Keywords:

yeast Candida famata riboflavin transcription factors iron-dependent regulation

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry
  • NZ1_9: Biotechnology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

woj. podkarpackie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Andriy Sybirnyy 

Number of co-investigators in the project: 5

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 975 600 PLN

Project start date (Y-m-d): 2019-02-13

Project end date (Y-m-d): 2022-02-12

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Spektrofluorymetr (180 000 PLN)
  2. Autoklaw laboratoryjny o pojemności 80L (120 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Book publications / chapters in book publications (2)
  1. Development of new dominant selectable markers for the nonconventional yeasts Ogataea polymorpha and Candida famata
    Authors:
    Bratiichuk D, Kurylenko O, Vasylyshyn R, Zuo M, Kang Y, Dmytruk K, Sibirny A.
    Academic press:
    Yeast (rok: 2020, tom: 37, strony: 505-513), Wydawca: Wiley & Sons Ltd.
    Status:
    Published
    DOI:
    10.1002/yea.3467 - link to the publication
  2. Modulation of the Purine Pathway for Riboflavin Productionin Flavinogenic Recombinant Strain of the Yeast Candida famata
    Authors:
    Dmytruk KV, Ruchala J, Fedorovych DV, Ostapiv RD, Sibirny AA.
    Academic press:
    Biotechnology Journal (rok: 2020, tom: 15, strony: 45298), Wydawca: Wiley (John Wiley & Sons)
    Status:
    Published
    DOI:
    10.1002/biot.201900468 - link to the publication
  3. Cloning of Genes Sef1 and Tup1 Encoding Transcriptional Activator and Global Repressor in the Flavinogenic Yeast Meyerozyma (Candida, Pichia) guilliermondii
    Authors:
    Fedorovych D, Boretsky V, Pynyaha Y., Bohovych I, Boretskya Y, Sibirny A
    Academic press:
    Cytology and Genetics (rok: 2020, tom: 54, strony: 413-419), Wydawca: Allerton Press, Inc.,
    Status:
    Published
    DOI:
    10.3103/S0095452720050072 - link to the publication
  4. Effect of Gene SFU1 on Riboflavin Synthesis in Flavinogenic Yeast Candida famata
    Authors:
    Petrovska Y, Lyzak O, Dmytruk K, Sibirny A.
    Academic press:
    Cytology and Genetics (rok: 2020, tom: 54, strony: 408–412), Wydawca: Allerton Press, Inc.,
    Status:
    Published
    DOI:
    10.3103/S0095452720050060 - link to the publication
  5. Expression of yeast homolog of the mammal BCRP gene coding for riboflavin efflux protein activates vitamin B2 production in the flavinogenic yeast Candida famata
    Authors:
    Tsyrulnyk A, Ruchala J, Fayura L, Dmytruk K, Fedorovyvh D, Sybirny A
    Academic press:
    Yeast (rok: 2020, tom: 37, strony: 467-473), Wydawca: Wiley & Sons Ltd.
    Status:
    Published
    DOI:
    10.1002/yea.3470 - link to the publication
  6. SEF1 and VMA1 Genes Regulate Riboflavin Biosynthesis in the Flavinogenic Yeast Candida Famata
    Authors:
    Andreieva Y, Lyzak O, Liu W, Kang Y, Dmytruk K, Sibirny A
    Academic press:
    Cytology and Genetics (rok: 2020, tom: 54, strony: 379-385), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.3103/S0095452720050023 - link to the publication
  1. Overexpression of Riboflavin Excretase Enhances Riboflavin Production in the Yeast Candida famata
    Authors:
    Tsyrulnyk AO, Fedorovych DV, Dmytruk KV, Sibirny AA
    Book:
    Methods in Molecular Biology (rok: 2021, tom: 2280, strony: 31-42), Wydawca: Springer, New York, NY
    Status:
    Published
  2. Recent Advances in Construction of the Efficient Producers of Riboflavin and Flavin Nucleotides (FMN, FAD) in the Yeast Candida famata
    Authors:
    Fedorovych DV, Dmytruk KV, Sibirny AA.
    Book:
    Methods in Molecular Biology (rok: 2021, tom: 2280, strony: 15-30), Wydawca: Springer, New York, NY
    Status:
    Published

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