Polymorphisms in otolin-1 genes in human and zebrafish - influence on function of the C1q-like domain in biomineralization of carbonate receptors of gravity
2017/27/N/NZ1/01319
Keywords
Descriptors
- NZ1_4: Biologia strukturalna
- NZ1_1: Biologia molekularna
- NZ1_5: Inżynieria genetyczna
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Politechnika Wrocławska
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 14 – announced on 2017-09-15
- Amount awarded
- 179 990 PLN
- Project start date
- 2018-07-24
- Project end date
- 2022-07-23
- Project duration
- 48 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Wirówka z chłodzeniem. Cost: 29 000 PLN
- Wytrząsarka Vortex BenchMixer z adapterem na jedną mikropłytkę.
Information in the final report
Publication in academic press/journals (2)
-
Molecular mechanism of calcium induced trimerization of C1q-like domain of otolin-1 from human and zebrafish
- Authors:
- Rafał Hołubowicz, Andrzej Ożyhar, Piotr Dobryszycki
- Academic press:
- Scientific Reports (year: 2021, volume: 11, pages: 12778), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1038/s41598-021-92129-8 – link to the publication
-
Natural Mutations Affect Structure and Function of gC1q Domain of Otolin-1
- Authors:
- Rafał Hołubowicz, Andrzej Ożyhar, Piotr Dobryszycki
- Academic press:
- International Journal of Molecular Sciences (year: 2021, volume: 22(16), pages: 9085), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms22169085 – link to the publication