Interplay of posttranslational redox cysteine modifications and metal ion binding as key to conformational and functional plasticity of innate immunity and cancer biomarkers - S100A8 and S100A9 proteins
2016/21/B/NZ1/02788
Keywords
Descriptors
- NZ1_3: Biofizyka
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Instytut Biochemii i Biofizyki PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
dr Aleksandra Wysłouch-Cieszyńska
Number of co-investigators in the project: 10
Call
OPUS 11 – announced on 2016-03-15
- Amount awarded
- 1 033 600 PLN
- Project start date
- 2017-03-02
- Project end date
- 2022-09-01
- Project duration
- 66 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Dwa zestawy komputerowe z monitorami, dyskami do przechowywania kopii zapasowych, UPS i oprogramowaniem zawierającym program kalkulacyjny Origin. Cost: 30 000 PLN
Information in the final report
Publication in academic press/journals (3)
-
ntracellular Protein S-Nitrosylation-A Cells Response to Extracellular S100B and RAGE Receptor
- Authors:
- Monika Zaręba-Kozioł, Michał Burdukiewicz, Aleksandra Wysłouch-Cieszyńska
- Academic press:
- Biomolecules (year: 2022, volume: 12(5), pages: 613-625), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/biom12050613 – link to the publication
-
Toward an understanding of the conformational plasticity of S100A8 and S100A9 Ca2+-binding proteins
- Authors:
- Magdalena Polakowska, Kamil Steczkiewicz, Roman H Szczepanowski, Aleksandra Wysłouch-Cieszyńska
- Academic press:
- Journal of Biological Chemistry (year: 2023, volume: 299(4), pages: 102952), Publisher: Elsevier
- Status:
- Published
-
Vimentin S-glutathionylation at Cys328 inhibits filament elongation and induces severing of mature filaments in vitro
- Authors:
- Magdalena Kaus-Drobek, Norbert Mucke, Roman H. Szczepanowski, Tatjana Wedig, Mariusz Czarnocki- Cieciura, Magdalena Polakowska, Harald Herrmann, Aleksandra Wysłouch-Cieszynska, Michał Dadlez
- Academic press:
- The FEBS Journal (year: 2020, volume: 287(24), pages: 5304-5322), Publisher: John Wiley & Sons
- Status:
- Published
- DOI:
- 10.1111/febs.15321 – link to the publication