Tick-borne encephalitis virus - search for mechanisms useful in treatment and prophylaxis.

2015/19/D/NZ6/01717

Keywords

Descriptors

  • NZ6_5: Wirusologia

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Voivodeship: pomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Ewelina Król

Number of co-investigators in the project: 4

Call

SONATA 10 – announced on 2015-09-15

Amount awarded
563 650 PLN
Project start date
2016-07-22
Project end date
2021-01-21
Project duration
54 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Spektrofluorymetr. Cost: 8 500 PLN
  2. System dokumentacji żeli ChemiDoc. Cost: 109 500 PLN
  3. Waga analityczna.
  4. Wirówka laboratoryjna z chłodzeniem.

Information in the final report

Publication in academic press/journals (4)

  1. The role of IFITM proteins in tick-borne encephalitis virus infection.

    Authors:
    Chmielewska AM., Gómez-Herranz M., Gach P., Nekulova M., Tyrakowska M., Lipińska AD., Rychłowski M., Hoffmann W., Król E., Vojtesek B., Sloan RD., Bieńkowska-Szewczyk K., Hupp T., Ball K.
    Academic press:
    Journal of Virology (year: 2021, volume: brak danych, pages: brak danych), Publisher: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/JVI.01130-21 – link to the publication
  2. Anti-Tick-Borne Encephalitis Virus Activity of Novel Uridine Glycoconjugates Containing Amide or/and 1,2,3-Triazole Moiety in the Linker Structure

    Authors:
    Gabriela Brzuska, Gabriela Pastuch-Gawolek, Monika Krawczyk, Boguslaw Szewczyk, Ewelina Krol
    Academic press:
    Pharmaceuticals (year: 2020, volume: 13(12), pages: 460), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ph13120460 – link to the publication
  3. Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus.

    Authors:
    Krol E., Wandzik I., Brzuska G., Eyer L., Růžek D., Szewczyk B.
    Academic press:
    Molecules (year: 2019, volume: 24, pages: 1129), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules24061129 – link to the publication
  4. Production and Biomedical Application of Flavivirus-like Particles.

    Authors:
    Krol E., Brzuska G., Szewczyk B.
    Academic press:
    Trends in Biotechnology (year: 2019, volume: 37(11), pages: 1202-1216), Publisher: Science Direct
    Status:
    Published
    DOI:
    10.1016/j.tibtech.2019.03.013 – link to the publication

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