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Information on the principal investigator and host institution

Information of the project and the call

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Proteomic and genetic analysis of the role of the EnvZ/OmpR pathway of Yersinia enterocolitica in the regulation of virulence properties and adaptation to stress conditions

2011/01/B/NZ6/01845

Keywords:

Yersinia enterocolitica enteropathogen EnvZ/OmpR system proteomic studies

Descriptors:

  • NZ6_4: Bacteriology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Warszawski, Wydział Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Katarzyna Brzostek 

Number of co-investigators in the project: 5

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 399 900 PLN

Project start date (Y-m-d): 2011-12-13

Project end date (Y-m-d): 2014-12-12

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Przystawka do fluorymetru (czytnik Infinite M200 PRO) (10 000 PLN)
  2. Zestaw do elektroforezy agarozowej wraz z zasilaczem BioRad (164-0300 MiniSub Cell/Power Pac Basic System) (5 000 PLN)
  3. Termocykler firmy BioRad (PTC-1148) (2 szt.) (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Impact of OmpR on the membrane proteome of Yersinia enterocolitica in different environments: repression of major adhesin YadA and heme receptor HemR
    Authors:
    Marta Nieckarz, Adrianna Raczkowska, Janusz Dębski, Michał Kistowski, Michał Dadlez, Jürgen Heesemann, Ombeline Rossier, Katarzyna Brzostek
    Academic press:
    Environmental Microbiology (rok: 2016, tom: 1, strony: 25), Wydawca: Society for Applied Microbiology and John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/1462-2920.13165 - link to the publication
  2. Regulatory protein OmpR influences the serum resistance of Yersinia enterocolitica O:9 by modifying the structure of the outer membrane
    Authors:
    Skorek K., Raczkowska A., Dudek B., Miętka K., Guz-Regner K., Pawlak A., Klausa E., Bugla-Płoskońska K., Brzostek K
    Academic press:
    PLOS ONE (rok: 2013, tom: 8(11): e79525, strony: 45309), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0079525 - link to the publication
  3. Expression of the AcrAB components of the AcrAB-TolC multidrug efflux pump of Yersinia enterocolitica is subject to dual regulation by OmpR
    Authors:
    Adrianna Raczkowska, Joanna Trzos, Olga Lewandowska, Marta Nieckarz, Katarzyna Brzostek
    Academic press:
    PLOS ONE (rok: 2015, ), Wydawca: Public Library of Science
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  1. OmpR-dependent variations in the susceptibility of Yersinia enterocolitica O9 to the bactericidal activity of serum involves modification of the proteins and lipopolysaccharide content of the outer membrane
    Authors:
    19.Skorek, K. Raczkowska A., Dudek B., Bugla-Płoskońska G., Brzostek K.
    Conference:
    Yersinia 11: The 11th International symposium on Yersinia. (rok: 2013, ), Wydawca: Cold Spring Harbor Laboratory
    Data:
    konferencja 24-28 czerwiec
    Status:
    Published
  2. Poszukiwanie genów regulonu OmpR Yersinia enterocolitica O:9 metodą mutagenezy transpozonowej
    Authors:
    Skorek Karolina, Raczkowska Adrianna, Brzostek Katarzyna
    Conference:
    XXVII Zjazd Polskiego Towarzystwa Mikrobiologów w Lublinie " Drobnoustroje bez granic" (rok: 2012, ), Wydawca: Polskie Towarzystwo Mikrobiologów
    Data:
    konferencja 5-8 wrzesień
    Status:
    Published

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