Search results

401. Modulation of the N-glycosylation as a tool to improve the CAR-T immunotherapy efficacy

Principal investigator: dr Agnieszka Graczyk-Jarzynka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 26, Panel: NZ7

402. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect…

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 26, Panel: NZ7

403. Metallacarborane-peptide amphiphiles as a new strategy in the fight against multidrug-resistant Gram-negative bacteria

Principal investigator: dr Krzysztof Konrad Fink

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: SONATA 19, Panel: NZ7

404. "One step to game changer": combined antimicrobial therapy based on AI and nanotechnology to combat challenging diabetes…

Principal investigator: dr Barbara Ewa Pucelik

Sieć Badawcza ŁUKASIEWICZ - Krakowski Instytut Technologiczny

Call: SONATA 19, Panel: NZ7

405. Does organic sulfur reduce the high fat diet-induced inflammation in benign prostate hyperplasia?

Principal investigator: dr Karolina Kowalska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: SONATA 19, Panel: NZ7

406. Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu…

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Call: OPUS 26, Panel: NZ7

407. Mucoadhesive nanospheres as an intravesical form of monomethyl auristatin E

Principal investigator: dr hab. Katarzyna Jelonek

Centrum Materiałów Polimerowych i Węglowych PAN

Call: OPUS 26, Panel: NZ7

408. EVALUATION OF THE USEFULNESS OF ADVANCED OXIDATION METHODS (AOP) ANDPHYTOREMEDIATION FOR REMOVAL OF MICROPLASTICS FROM W…

Principal investigator: prof. Joanna Karpińska

Uniwersytet w Białymstoku, Wydział Chemii

Call: OPUS 26, Panel: ST10

409. Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co…

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 26, Panel: NZ7

410. PROteolysis TArgeting Chimeras (PROTACs) intended to knock down excessive amyloidogenic proteins, human islet amyloid po…

Principal investigator: dr hab. Elżbieta Jankowska

Uniwersytet Gdański, Wydział Chemii

Call: OPUS 26, Panel: NZ7

411. Synthesis and application of new mixed-mode materials to study the metabolism of drugs used in Poland for the treatment …

Principal investigator: dr hab. Sylwia Studzińska

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: OPUS 26, Panel: NZ7

412. Bacterial membrane carriers targeting tumor-associated microbes for advanced cancer therapy

Principal investigator: dr Monika Kluzek

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Call: OPUS 26, Panel: NZ7

413. Application of superparamagnetic iron oxide nanoparticles (SPION) in inhaled theranostic systems containing antifungal d…

Principal investigator: dr Gabriela Małgorzata Wyszogrodzka-Gaweł

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 19, Panel: NZ7

414. Spatiotemporal control of growth factor release from porous composite scaffolds for chronic wound healing.

Principal investigator: dr Tomasz Marek Urbaniak

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Call: SONATA 19, Panel: NZ7

415. The Impact of Undernutrition on Host Microbiome: the Messenger Role of Bacterial Extracellular Vesicles.

Principal investigator: dr Agnieszka Maria Razim

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: SONATA 19, Panel: NZ7

416. VAMPIRE-AI: Visualisation and quAntification of Microvascular PerfusIon in Radiology and surgEry with Artificial Intelli…

Principal investigator: prof. Ronald Jan Hendrik Borra

Gdański Uniwersytet Medyczny

Call: Profesura NAWA 2022, Panel: NZ7

417. Functional and structural analysis of anticancer drugs as protein biosynthesis inhibitors

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Call: OPUS 26, Panel: NZ7

418. Evaluating the antibacterial activity of the bacteriophage protein targeting Staphylococcus aureus, including drug-resis…

Principal investigator: dr Zuzanna Maria Kaźmierczak

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: SONATA 19, Panel: NZ7

419. A new generation of scaffolds based on curdlan and whey protein isolate obtained by electrospinning for the treatment of…

Principal investigator: dr Katarzyna Klimek

Uniwersytet Medyczny w Lublinie

Call: SONATA 19, Panel: NZ7

420. Long-term impact of physical activity on the prevention of cognitive function decline

Principal investigator: prof. Jarosław Mirosław Walkowiak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

Call: PRELUDIUM BIS 5, Panel: NZ7

421. Macrocyclic peptides for targeting of membrane-anchored serine protease

Principal investigator: dr hab. Paulina Maria Kasperkiewicz-Wasilewska

Politechnika Wrocławska

Call: PRELUDIUM BIS 5, Panel: NZ7

422. Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem…

Principal investigator: dr hab. Małgorzata Firczuk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM BIS 5, Panel: NZ7

423. Amorphous dispersions as active and effective systems for printed dressings

Principal investigator: prof. Judyta Agnieszka Cielecka-Piontek

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: PRELUDIUM BIS 5, Panel: NZ7

424. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Call: SONATA BIS 13, Panel: NZ7

425. The role of free fatty acid receptors in pathophysiology of the functional gastrointestinal tract disorders: new therapi…

Principal investigator: dr hab. Maciej Stanisław Sałaga

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM BIS 5, Panel: NZ7

426. One health surveillance approach on marine mammal, marine environmental and human antimicrobial resistance on the North …

Principal investigator: dr Iwona Joanna Pawliczka vel Pawlik

Uniwersytet Gdański, Wydział Oceanografii i Geografii

Call: JPIAMR ACTION Call 2023, Panel: NZ7

427. Lavender flower as a source of postbiotic metabolites modulating functions of intestinal and blood-brain barriers

Principal investigator: prof. Sebastian Granica

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: SONATA BIS 13, Panel: NZ7

428. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain…

Principal investigator: dr Bartosz Sebastian Pomierny

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA BIS 13, Panel: NZ7

429. Directed screening and evaluation of novel bactericidal compounds active againsttubercle bacilli and Mycobacterium absce…

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Call: OPUS 25, Panel: NZ7

430. Compounds modulating function of telomeric proteins TRF1 and TRF2

Principal investigator: prof. Maciej Wojciech Bagiński

Politechnika Gdańska, Wydział Chemiczny

Call: OPUS 25, Panel: NZ7

431. Effect of a short-term multi-strain probiotic supplementation on the exercise-associated gastrointestinal disturbances i…

Principal investigator: dr Natalia Maria Główka

Akademia Wychowania Fizycznego im. Eugeniusza Piaseckiego w Poznaniu

Call: PRELUDIUM 22, Panel: NZ7

432. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac…

Principal investigator: dr hab. Małgorzata Firczuk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 25, Panel: NZ7

433. Inactivation of intracellular Staphylococcus aureus and staphylococcal enterotoxins with photoactivated compounds in mod…

Principal investigator: dr hab. Joanna Nakonieczna

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: OPUS 25, Panel: NZ7

434. Neuroprotective effect of SGLT2i: direct influence on amyloid-β related pathology

Principal investigator: Agnieszka Pawlos

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM 22, Panel: NZ7

435. Curdlan-based biomaterial as a nanostructure carrier for controlled and targeted drug delivery in the treatment of deep …

Principal investigator: dr Aleksandra Nurzyńska

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM 22, Panel: NZ7

436. Anticancer potential of TMPyP4 porphyrin in breast cancer photodynamic therapy and evaluation of the treatment safety

Principal investigator: prof. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: OPUS 25, Panel: NZ7

437. Do metal nanoparticles affect the biosynthesis of bioactive plant metabolites? - studies on an in vitro culture model of…

Principal investigator: dr hab. Agnieszka Szopa

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 25, Panel: NZ7

438. The cross-talk between 5-HTR2A and mGluR2 as a window for antidepressant effects of psilocybin.

Principal investigator: prof. Andrzej Mikołaj Pilc

Instytut Farmakologii PAN

Call: OPUS 25, Panel: NZ7

439. Understanding the contribution of immunoproteasome activation to the neuropathic pain development.

Principal investigator: dr Natalia Eleonora Małek-Chudzik

Politechnika Wrocławska

Call: OPUS 25, Panel: NZ7

440. Amorphous Senolytics: A Breakthrough Approach in Senescence Modulation and Age-Related Disease Treatment

Principal investigator: Szymon Sip

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: PRELUDIUM 22, Panel: NZ7

441. Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

Principal investigator: Patryk Pyka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 22, Panel: NZ7

442. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design…

Principal investigator: Emilia Aleksandra Sługocka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 22, Panel: NZ7

443. Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to …

Principal investigator: Marika Anna Frańczak

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: PRELUDIUM 22, Panel: NZ7

444. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 25, Panel: NZ7

445. Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen…

Principal investigator: prof. Ryszard Józef Ostaszewski

Instytut Chemii Organicznej Polska Akademia Nauk

Call: OPUS 25, Panel: NZ7

446. The Way to longevity - Effects of resveratrol or/and nanodiamonds on sirtuin activity in Acheta domesticus

Principal investigator: Patrycja Joanna Ziętara-Krzyk

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

Call: PRELUDIUM 22, Panel: NZ7

447. Assessment of twin screw extrusion potential as a continuous and scalable method of mechanochemical synthesis of active …

Principal investigator: Anna Magdalena Gołkowska

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Farmaceutyczny

Call: PRELUDIUM 22, Panel: NZ7

448. Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

Principal investigator: Alex Jun Matsuda

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: PRELUDIUM 22, Panel: NZ7

449. The Role of the Mitochondrial Unfolded Protein Response (UPRmt) in Endothelial Function: a Possible Novel Target for the…

Principal investigator: Sylwester Tycjan Mosiołek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: PRELUDIUM 22, Panel: NZ7

450. unESKAPEable. Innovative antibiotics leads based on bifunctionalsed metallacarboranes to combat ESKAPE pathogens.

Principal investigator: Jakub Cebula

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 22, Panel: NZ7

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