Projects funded by the NCN

The role of NFAT (nuclear factor of activated T cells) and GM-CSF (granulocyte/macrophage colony stimulating factor) sig...

Call: OPUS 8 , Panel: NZ3

Principal investigator: dr Aleksandra Ellert-Miklaszewska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Structural and functional characterisation of the photosynthetic apparatus of an extremophilic red microalga Cyanidiosch...

Call: OPUS 8 , Panel: NZ1

Principal investigator: dr hab. Joanna Kargul

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

The mechanism of neurotoxic action of benzophenone-3

Call: OPUS 8 , Panel: NZ7

Principal investigator: prof. Bogusława Budziszewska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

The influence of nanoparticles on beta-amyloid removal by microglia cells

Call: PRELUDIUM 6 , Panel: NZ7

Principal investigator: Katarzyna Sikorska

Instytut Chemii i Techniki Jądrowej

Neuronal and nonneuronal mechanisms of Bont/A effects in neuropathic pain development - behavioral and biochemical studi...

Call: HARMONIA 5 , Panel: NZ4

Principal investigator: dr hab. Joanna Mika

Instytut Farmakologii PAN

Application of DNase I-seq to identify transcription factors participating in alternative microglia activation in respon...

Call: OPUS 5 , Panel: NZ2

Principal investigator: dr hab. Michał Dąbrowski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Biological activity of secondary metabolites produced by selected species of baltic dinoflagellates, diatoms and cyanoba...

Call: PRELUDIUM 5 , Panel: NZ8

Principal investigator: Adam Żak

Instytut Oceanologii Polskiej Akademii Nauk

Effect of allelopathic interactions on the occurence of massive cyanobacterial blooms.

Call: PRELUDIUM 5 , Panel: ST10

Principal investigator: Sylwia Śliwińska

Uniwersytet Gdański, Wydział Oceanografii i Geografii

Optimization of pigment biosynthesis and extraction form diatom cultures

Call: PRELUDIUM 4 , Panel: ST8

Principal investigator: Krystian Miazek

Politechnika Łódzka, Wydział Inżynierii Procesowej i Ochrony Środowiska

Examine the importance of intracellular pathways in the action of opioids in microglial cells in vitro

Call: PRELUDIUM 4 , Panel: NZ3

Principal investigator: Katarzyna Popiołek-Barczyk

Instytut Farmakologii PAN

The role of glioma-derived signaling molecules in polarization of macrophages and shaping immune microenvironment

Call: MAESTRO 2 , Panel: NZ3

Principal investigator: prof. Bożena Kamińska-Kaczmarek

INSTYTUT BIOLOGII DOŚWIADCZALNEJ PAN IM.M.NENCKIEGO

Role of GM-CSF (granulocyte-macrophage colony stimulating factor) in macrophage recruitment and glioma growth.

Call: PRELUDIUM 2 , Panel: NZ1

Principal investigator: Małgorzata Sielska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Identifying the molecular mechanisms responsible for pro-regenerative role of microglia/macrophages in remyelination of ...

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr Małgorzata Zawadzka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The mechanism of hydrogen in a closed syystem using microalgae of the genus Platymonas Subcordiformis using water from B...

Call: PRELUDIUM 2 , Panel: ST8

Principal investigator: Magda Dudek

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauk o Środowisku

The role of transcription factors Stat1 and Stat3 in transcriptional regulation of uba7 and jmjd3, crucial mediators of ...

Call: PRELUDIUM 2 , Panel: NZ1

Principal investigator: Piotr Przanowski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Elucidating the role of SorLA receptor in shaping immunosuppressive character of glioma microenvironment

Call: PRELUDIUM 22 , Panel: NZ4

Principal investigator: Paulina Kamińska

Uniwersytet Warszawski, Wydział Biologii

EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

Call: SONATA 18 , Panel: NZ3

Principal investigator: dr Aleksandra Rutkowska

Gdański Uniwersytet Medyczny, Centrum Chorób Mózgu

Development of the knowledge on the role of GPR18 ligands as a microglia-targeted strategy in the regulation of neuroinf...

Call: SONATA 17 , Panel: NZ3

Principal investigator: dr Ewelina Honkisz-Orzechowska

Uniwersytet Jagielloński, Collegium Medicum

Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Katarzyna Kieć-Kononowicz

Uniwersytet Jagielloński, Collegium Medicum

New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

Call: OPUS 22 , Panel: NZ4

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Porphyromonas gingivalis as an etiologic factor in the development of neuroinflammation and neurodegeneration - studies ...

Call: OPUS 22 , Panel: NZ6

Principal investigator: prof. Magdalena Chadzińska

Uniwersytet Jagielloński, Wydział Biologii

New strategies in the pharmacotherapy of neuropathic pain based on modulation of the chemokine system and its influence ...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Joanna Mika

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The roles and therapeutic potential of distinct dystrophin and utrophin isoforms in the central and peripheral nervous s...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Patryk Konieczny

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Stimulation and regulation of growth of biofilm and microalgae and cyanobacteria in photosynthetic microbial fuel cell

Call: OPUS 21 , Panel: NZ9

Principal investigator: prof. Marcin Zieliński

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Geoinżynierii

Single cell multi-omics in defining how specific oncogenic alterations shape the immune microenvironment and responses t...

Call: OPUS 20 , Panel: NZ4

Principal investigator: prof. Bożena Kamińska-Kaczmarek

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

New role for myosin VI in structural organization and function of epididymal epithelium in mouse

Call: OPUS 20 , Panel: NZ4

Principal investigator: dr hab. Marta Lenartowska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the ...

Call: OPUS 19 , Panel: NZ7

Principal investigator: dr Natalia Małek-Chudzik

Politechnika Wrocławska

VPS10P domain receptors in phenotypic polarization of astrocytes and microglia in the diseased brain.

Call: OPUS 19 , Panel: NZ3

Principal investigator: dr Anna Malik

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi...

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr hab. Joanna Mika

Instytut Farmakologii PAN

Identification and characteristics of mechanisms governing triacylglycerol homeostasis in oleaginous microalgae and oil ...

Call: OPUS 19 , Panel: NZ9

Principal investigator: dr hab. Krzysztof Zienkiewicz

Uniwersytet Mikołaja Kopernika w Toruniu, Interdyscyplinarne Centrum Nowoczesnych Technologii

Oil producing diacylglycerol acyltransferases encoded by the genome of oleaginous microalga Nannochloropsis oceanica – f...

Call: OPUS 18 , Panel: NZ9

Principal investigator: dr hab. Krzysztof Zienkiewicz

Uniwersytet Mikołaja Kopernika w Toruniu, Interdyscyplinarne Centrum Nowoczesnych Technologii

Characterisation of the molecular mechanisms of heavy metals adaptation in extremophilic red microalgae Cyanidiales

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr hab. Joanna Kargul

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Can cyanobacteria and microalgae in the air of the Baltic coastal zone be a potential threat to human health?

Call: PRELUDIUM 17 , Panel: ST10

Principal investigator: Kinga Wiśniewska

Uniwersytet Gdański, Wydział Oceanografii i Geografii

Regulation of chromatin accessibility in the hypoxic tumour microenvironment of glioblastoma

Call: OPUS 17 , Panel: NZ1

Principal investigator: dr Katarzyna Leszczyńska

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Assessment of virulence potential of Prototheca microalgae, opportunistic pathogens of humans and animals – in vitro and...

Call: OPUS 17 , Panel: NZ6

Principal investigator: dr Tomasz Jagielski

Uniwersytet Warszawski, Wydział Biologii

Determination of the mechanisms and possibility of central nervous system regeneration using mesenchymal stem cells and ...

Call: OPUS 16 , Panel: NZ3

Principal investigator: prof. Marcin Majka

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Lekarski

Simultaneous transcriptomic and immune phenotyping of glioma-infiltrating microglia and macrophages at the single-cell l...

Call: PRELUDIUM 16 , Panel: NZ3

Principal investigator: Natalia Ochocka-Lewicka

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

The role of BET family proteins in microglia-dependent neurodegeneration; relevance to Alzheimer's disease

Call: OPUS 16 , Panel: NZ4

Principal investigator: dr hab. Grzegorz Czapski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Substrate specificity of LPCATs from photosynthetic oleaginous microalgae in forward and reverse reactions and character...

Call: SHENG 1 , Panel: NZ3

Principal investigator: prof. Antoni Banaś

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Evaluation of therapeutic role of novel positive allosteric modulators of GABA-A receptor in ischemic brain stroke

Call: SONATA BIS 8 , Panel: NZ7

Principal investigator: dr Monika Marcinkowska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Western diet as a potent risk factor of Alzheimer's disease progression: influence of a long-term Western diet feeding o...

Call: PRELUDIUM 15 , Panel: NZ7

Principal investigator: Angelika Więckowska-Gacek

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Histone deacetylase inhibitors as potential modulatory factors of inflammatory response induced in the rat brain after n...

Call: OPUS 14 , Panel: NZ3

Principal investigator: dr hab. Małgorzata Nałęcz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective ...

Call: OPUS 14 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Kuter-Nowak

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Application of lithium selenolate as an example of efficient IRC reaction catalyst - synthesis of substituted 5-7 member...

Call: OPUS 14 , Panel: ST5

Principal investigator: dr Szymon Buda

Uniwersytet Jagielloński, Wydział Chemii

Influence of the disintegration method on the amount of lipids derived from microalgae biomass of Botryococcus braunii a...

Call: PRELUDIUM 12 , Panel: ST8

Principal investigator: Magdalena Rokicka

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauk o Środowisku

Synthesis and physicochemical characteristics of novel hybrid polyelectrolyte microcapsules with entrapped unicellular a...

Call: SONATA 11 , Panel: ST8

Principal investigator: dr Anna Dawiec-Liśniewska

Politechnika Wrocławska

Search for new targets for an effective therapy of neuropathic pain and enhancement of opioids effects basing on the exa...

Call: OPUS 11 , Panel: NZ4

Principal investigator: prof. Joanna Mika

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of the neuron-microglia CX3CL1-CX3CR1 and CD200-CD200R protein systems in molecular mechanisms of antipsychotic...

Call: OPUS 10 , Panel: NZ7

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Dissecting pathomechanisms of idiopathic form of Parkinson's Disease using induced pluripotent stem cells technology

Call: OPUS 9 , Panel: NZ5

Principal investigator: prof. Marcin Majka

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: dr Ewa Trojan

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk