Projects funded by the NCN

Pharmacotherapeutic mechanisms, spectroscopic signatures, and nanomechanics of dysfunctional endothelium in liver steato...

Call: SYMFONIA 3 , Panel: NZ4

Principal investigator: prof. Stefan Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET), Pracownia Farmakologii Doświadczalnej Śródbłonka

Air Pollution versus Autoimmunity: Role of multiphase aqueous Inorganic Chemistry (APARIC)

Call: SYMFONIA 3 , Panel: ST5

Principal investigator: prof. Rudi van Eldik

Uniwersytet Jagielloński, Wydział Chemii

Does PGE2 increase adhesion of platelets to endothelium in flow conditions via activation of EP3 receptor? In vitro and ...

Call: PRELUDIUM 8 , Panel: NZ3

Principal investigator: dr Marcin Talar

Uniwersytet Medyczny w Łodzi, Katedra Nauk Biomedycznych

Nitric oxide delivery system for biomedical applications

Call: OPUS 8 , Panel: ST5

Principal investigator: prof. Adam Patkowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Nanobiomedyczne

The role of urokinase-type plasminogen activator receptor in the process of endothelial microparticle formation and inte...

Call: PRELUDIUM 8 , Panel: NZ5

Principal investigator: Martyna Durak-Kozica

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Non-quinazoline antagonists of apha1 and 5-HT2A receptors with pleiotropic effects as a new perspective for hypertension...

Call: SONATA 8 , Panel: NZ7

Principal investigator: dr Monika Kubacka

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Comparison of the effects of endurance and endurance-strength training programs on the level of endothelial dysfunction ...

Call: OPUS 7 , Panel: NZ7

Principal investigator: prof. Jarosław Walkowiak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

Research on human eosinophils as a potential therapeutic target.

Call: PRELUDIUM 7 , Panel: NZ7

Principal investigator: Marek Grosicki

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Study of the influence of the drug physicochemical properties on its endothelial distribution and binding ability to pla...

Call: PRELUDIUM 7 , Panel: NZ7

Principal investigator: Anna Gonciarz-Dytman

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Label-free imaging of subcelluar structures of endotelium using Confocal Raman Spectroscopy supported by FT-IR Spectrosc...

Call: PRELUDIUM 5 , Panel: ST4

Principal investigator: dr Katarzyna Majzner

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Multiparameter imaging of cells by using vibrational spectroscopy, AFM and SNOM: analysis of biochemical changes in sing...

Call: MAESTRO 4 , Panel: ST4

Principal investigator: prof. Małgorzata Barańska

Uniwersytet Jagielloński, Wydział Chemii

Studies on antiplatelet and antithrombotic activity of CO-relasing molecules (CO-RM)

Call: HARMONIA 4 , Panel: NZ7

Principal investigator: prof. Stefan Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The role of endothelial barrier function in the pathogenesis of atherosclerosis and its modulation by the immune system

Call: SONATA 1 , Panel: NZ5

Principal investigator: dr Maciej Chałubiński

Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski, Klinika Chorób Wewnętrznych i Farmakologii Klinicznej

Oxidative metabolism of endothelial cells under hypoxic conditions

Call: PRELUDIUM 4 , Panel: NZ3

Principal investigator: Agnieszka Kozieł

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The role of microparticles in pathomechanisms of diabetic retinopathy - analysis of intercellular communication mechanis...

Call: OPUS 4 , Panel: NZ5

Principal investigator: dr hab. Ewa Stępień

Uniwersytet Jagielloński-Collegium Medicum, Collegium Medicum, Wydział Lekarski

May post-translational non-enzymatic modifications of platelet proteins contribute to altered platelet adhesion to endot...

Call: MAESTRO 3 , Panel: NZ5

Principal investigator: prof. Cezary Watała

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Epigentic regulation of angiogenesis induced by changes in methylation of histone proteins as a chance for new therapies...

Call: OPUS 3 , Panel: NZ2

Principal investigator: dr Aneta Balcerczyk

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Physicochemical studies on membrane and intracellular environment of endothelium

Call: PRELUDIUM 3 , Panel: ST4

Principal investigator: Aleksandra Jaworska

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków

Development of EPR oximetry methodology for evaluation of endothelial action of drugs

Call: SONATA 3 , Panel: NZ7

Principal investigator: dr Patrycja Kaczara

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The effect of omega-3 polyunsaturated acids supplementation on endothelial function, oxidative stress, platelet aggregat...

Call: OPUS 2 , Panel: NZ5

Principal investigator: dr hab. Grzegorz Gajos

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

Endothelial bioenergetics as a novel target for vascular protection – unveiling the mitochondrial mechanisms of lipid-lo...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Alicja Braczko

Gdański Uniwersytet Medyczny, Wydział Lekarski

The Role of the Mitochondrial Unfolded Protein Response (UPRmt) in Endothelial Function: a Possible Novel Target for the...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Sylwester Mosiołek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Cross-talk between endothelium and perivascular adipose tissue upon inflammation: high-resolution imaging of adipocytes ...

Call: PRELUDIUM 22 , Panel: ST4

Principal investigator: Ewa Stanek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Impact of uremic carbamylation on RAA system and endothelial dysfunction

Call: OPUS 24 , Panel: NZ4

Principal investigator: prof. Piotr Mydel

Uniwersytet Jagielloński

Specific immune signatures of T cells as biomarkers of the post-COVID Syndrome and predictors of long-term health dysfun...

Call: PRELUDIUM BIS 4 , Panel: NZ6

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

The impact of physical activity on brain resilience to chronic stress and the mediating role of blood-brain barrier.

Call: OPUS 24 , Panel: NZ7

Principal investigator: dr Marta Nowacka-Chmielewska

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach, Instytut Fizjoterapii i Nauk o Zdrowiu

In the search of specific oxylipin fingerprint reflecting the development of endothelial dysfunction with the use of non...

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Agnieszka Kij

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The assessment of the susceptibility of the lung endothelium to infections with respiratory viruses and its involvement ...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Maciej Chałubiński

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Role of endothelial cells in development of post-inflammatory dilated cardiomyopathy

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: dr hab. Przemysław Błyszczuk

Uniwersytet Jagielloński, Collegium Medicum

Multimodal approach for a comprehensive assessment of (dys)functional endothelial phenotype in isolated blood vessels

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Marta Pacia

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Metabolic reprogramming in age-dependent endothelial dysfunction and vascular stiffness; novel mechanism of 'inflamm-age...

Call: MAESTRO 13 , Panel: NZ4

Principal investigator: prof. Stefan Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

PDMS-based specially designed microfluidic channel lined with primary endothelial cells: a novel tool for experimental p...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Stefano Rocchetti

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Assessment of the endothelial adherens junctions, neuronal damage and the fetal blood-brain barrier integrity in respons...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Natalia Misan

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The role of rhinovirus in the limitation of infection of the human lung endothelium with low pathogenic coronavirus in t...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Mateusz Gawrysiak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

The role of lactate dehydrogenase A in development of endothelial dysfunction in murine model of heart failure

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Agnieszka Karaś

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Vascular endothelium-supporting materials: Understanding the structural and physicochemical requirements

Call: OPUS 20 (LAP) , Panel: ST5

Principal investigator: prof. Tomasz Ciach

Politechnika Warszawska

Molecular background of microvascular complications in HNF1A-MODY patients: induced pluripotent stem cells as disease mo...

Call: SONATA BIS 10 , Panel: NZ3

Principal investigator: dr Neli Kachamakova-Trojanowska

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Novel strategies for pharmacological modulation of platelet-derived microparticles - effects on endothelium

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Agnieszka Pełesz

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The proangiogenic functions of PIM kinases in plasma cell myeloma

Call: ETIUDA 8 , Panel: NZ5

Principal investigator: Filip Garbicz

Instytut Hematologii i Transfuzjologii

Which patients with rheumatoid arthritis or axial spondyloarthritis without classical cardiovascular risk factors have m...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Jarosław Nowakowski

Uniwersytet Jagielloński, Collegium Medicum

Function and phenotype of liver sinusoidal endothelial cells (LSECs) and their role in liver dysfunction development in ...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Kamila Wojnar-Lasoń

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

DHA/EPA and changes of peripheral blood cell epigenetics as well as the level of endothelial and pancreatic beta cell sp...

Call: MAESTRO 1 , Panel: NZ2

Principal investigator: prof. Aldona Dembińska-Kieć

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydzial Lekarski

Ecto-enzymes in interactions of vascular endothelium with blood circulating cells in physiology, pathology and therapy; ...

Call: SONATA 15 , Panel: NZ3

Principal investigator: dr Barbara Kutryb-Zając

Gdański Uniwersytet Medyczny, Wydział Lekarski

Comparative evaluation of effects of tyrosine kinase inhibitors (TKIs) on endothelial function in vivo in mice

Call: PRELUDIUM 17 , Panel: NZ5

Principal investigator: Brygida Marczyk

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The role of molecular composition of endothelial and pancreatic beta-cell extracellular vesicle in diabetic endothelial ...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr hab. Ewa Stępień

Uniwersytet Jagielloński

Cellular mechanisms and effects in vivo of selective lactate dehydrogenase A inhibitors in experimental models of mesoth...

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Ryszard Smoleński

Gdański Uniwersytet Medyczny, Wydział Lekarski

Glycocalyx damage - the first stage of pathomechanism of endothelial dysfunction; measurements using capillary electroph...

Call: PRELUDIUM 16 , Panel: NZ7

Principal investigator: dr Karolina Matyjaszczyk-Gwarda

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Ectosomal alpha-v beta-3 and alpha-v beta-5 as potential proangiogenic factors during melanoma progression

Call: PRELUDIUM 16 , Panel: NZ4

Principal investigator: dr Magdalena Surman

Uniwersytet Jagielloński, Wydział Biologii

Endothelial cells in the composition of hematopoietic niche: the versatile choir or specialized soloists?

Call: MAESTRO 10 , Panel: NZ3

Principal investigator: prof. Alicja Józkowicz

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The assesment of endothelium considering role of endothelial progenitor cells and leukotrienes synthesis in patients wit...

Call: PRELUDIUM 14 , Panel: NZ5

Principal investigator: Agnieszka Wachsmann

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski