Projects funded by the NCN

Targeted inhibition of STATs and IRFs as a novel treatment strategy in cardiovascular disease

Call: OPUS 9 , Panel: NZ2

Principal investigator: prof. Johannes Antonius Bluijssen (Bluyssen)

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Aromatic aminotransferases from Candida albicans as molecular targets for antifungal chemotherapy.

Call: OPUS 9 , Panel: NZ6

Principal investigator: dr Iwona Aniela Gabriel

Politechnika Gdańska, Wydział Chemiczny

Mechanisms underlying the targeting of coding sequence repeats by microRNA-like inhibitors

Call: OPUS 8 , Panel: NZ1

Principal investigator: dr Agnieszka Fiszer

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

Call: HARMONIA 6 , Panel: NZ5

Principal investigator: dr Tomasz Artur Stokłosa

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Hydrogel microspheres containing dextran-based nanoparticles. Study on targeting effect in novel anticancer drug deliver...

Call: PRELUDIUM 7 , Panel: NZ5

Principal investigator: Aleksandra Anna Kulikowska

Politechnika Warszawska, Wydział Inżynierii Chemicznej i Procesowej

Analysis of relations on the level of metabolome, miRNome, and transcriptome of human renal cancer: towards identificati...

Call: OPUS 7 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Piekiełko-Witkowska

Centrum Medyczne Kształcenia Podyplomowego

Targeted genomics of cardiovascular disease - multivariable genetic model of perioperative and long-term cardiovascular ...

Call: OPUS 5 , Panel: NZ5

Principal investigator: prof. Marek Jan Sanak

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Characteristics of the cell wall hydrolases of pathogenic bacteria Listeria monocytogenes and their partcipation in the ...

Call: OPUS 5 , Panel: NZ6

Principal investigator: dr hab. Magdalena Anna Popowska

Uniwersytet Warszawski, Wydział Biologii

Identification of triple negative breast cancer with inactive DNA damage repair pathway by homologous recombination base...

Call: SONATA 3 , Panel: NZ5

Principal investigator: dr Paweł Wenancjusz Domagała

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Next-Generation Exosome Therapy: Engineering NK Cell-Derived Vesicles for Targeted Cancer Treatment

Call: SONATINA 9 , Panel: NZ6

Principal investigator: dr Daria Nawrocka

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Identifying early biomarkers and molecular targets for therapeutic intervention in right ventricular dysfunction

Call: OPUS 28 , Panel: NZ5

Principal investigator: prof. Przemysław Błyszczuk

Uniwersytet Jagielloński

Molecular insights into NAD+ metabolism in Huntington's disease: role in pathophysiology and preclinical assessment of t...

Call: OPUS 28 , Panel: NZ5

Principal investigator: dr hab. Marta Urszula Tomczyk

Gdański Uniwersytet Medyczny

Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c...

Call: OPUS 28 , Panel: NZ7

Principal investigator: dr hab. Monika Emilia Marcinkowska

Uniwersytet Jagielloński

M6A RNA methylation signatures as a targets for HPV-dependent HNSCC therapy

Call: OPUS 27 , Panel: NZ5

Principal investigator: Kamila Ostrowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Identification of circulating biomarkers for monitoring anti-CD19 CAR-T cell treatment response in patients with aggress...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Monika Szelest

Uniwersytet Medyczny w Lublinie

Precision double strike against non-small cell lung cancer. Insights into multidirectional therapies and the landscape o...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Katarzyna Anna Malarz

Politechnika Śląska

Proteomic predictors of metastasis in colorectal cancer – a validation study

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Anna Wojakowska

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Exploring genetic resources of flax via genetic and metabolic markers as a means for targeted breeding towards improved ...

Call: OPUS 27 , Panel: NZ9

Principal investigator: dr hab. Anna Małgorzata Kulma

Uniwersytet Wrocławski

CD147 as a novel multifunctional modulator of podocyte metabolism and exosome biogenesis: Identification of new molecula...

Call: OPUS 27 , Panel: NZ4

Principal investigator: dr hab. Agnieszka Piwkowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Anna Krętowska-Grunwald

Uniwersytet Medyczny w Białymstoku

Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

Call: OPUS 24 , Panel: NZ5

Principal investigator: dr hab. Marcin Łukasz Poręba

Politechnika Wrocławska

Customized DNA-based nanocarriers to boost heart healing

Call: WEAVE-UNISONO , Panel: NZ7

Principal investigator: dr Monika Bzowska

Uniwersytet Jagielloński

Investigating the role of fibroblast growth factor receptors and STAT transcription factors in the targeted therapy of a...

Call: PRELUDIUM BIS 4 , Panel: NZ5

Principal investigator: prof. Ewa Teresa Marcinkowska

Uniwersytet Wrocławski, Wydział Biotechnologii

Modifiers of Muscleblind-like genes expression in health and disease.

Call: SONATA BIS 12 , Panel: NZ5

Principal investigator: dr hab. Ewa Agnieszka Stępniak-Konieczna

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

Targeting of metabolic and transcriptomic cross-talk between leukemic cells and macrophages as a therapeutic strategy in...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr Baran Natalia

Instytut Hematologii i Transfuzjologii

Mechanisms and consequences of CD19 loss in B-acute lymphoblastic leukaemia patients relapsing after CD19-CAR-T cell the...

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: prof. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Studies on the prevalence and properties of peptidoglycan peptidases as potential antimicrobial agents with targeted spe...

Call: OPUS 22 , Panel: NZ6

Principal investigator: dr hab. Benedykt Władyka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The role of NPM1 as biomarker of the targeted therapy efficacy in chronic lymphocytic leukemia patients

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: prof. Krzysztof Georgios Giannopoulos

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr Maciej Stefan Szydłowski

Instytut Hematologii i Transfuzjologii

In the search of specific oxylipin fingerprint reflecting the development of endothelial dysfunction with the use of non...

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Agnieszka Róża Kij

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Targeting of HSF1 as a therapeutic approach to inhibit the progression of hormone-dependent breast cancer.

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr Natalia Vydra

Narodowy lnstytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy lnstytut Badawczy, Oddział w Gliwicach

Searching for new therapeutic targets in polyglutamine diseases

Call: OPUS 22 , Panel: NZ2

Principal investigator: dr hab. Marta Olejniczak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

The biological role of sRNA OmrA and its impact on the level of virulence and adaptability of Yersinia enterocolitica en...

Call: PRELUDIUM BIS 3 , Panel: NZ6

Principal investigator: dr hab. Adrianna Dorota Raczkowska

Uniwersytet Warszawski, Wydział Biologii

Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Anna Piotrowska-Murzyn

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Mechanisms involved in heme acquisition - potential targets for therapies directed towards reduction of Porphyromonas gi...

Call: OPUS 21 , Panel: NZ6

Principal investigator: dr Michał Sylwester Śmiga

Uniwersytet Wrocławski, Wydział Biotechnologii

MicroRNAome maturation control and its application in selective targeting of cancer stem cells

Call: OPUS 20 , Panel: NZ5

Principal investigator: dr Jakub Godlewski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Identification of the interdependence between SWI/SNF-type chromatin remodeling complex, metabolism control and RNA modi...

Call: OPUS 20 , Panel: NZ5

Principal investigator: prof. Tomasz Jacek Sarnowski

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Identification of surface proteins as alternate targets for CAR-T therapy against CD19-negative tumors.

Call: PRELUDIUM BIS 2 , Panel: NZ6

Principal investigator: dr hab. Magdalena Hanna Winiarska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

The use of surface proteins to capture cancer cells with functionalized magnetic nanoparticles as an innovative theranos...

Call: OPUS 20 , Panel: NZ5

Principal investigator: dr hab. Joanna Danuta Dulińska-Litewka

Uniwersytet Jagielloński, Wydział Chemii

Identification of potential markers aiming early diagnostics of progression and tailoring metastasis-oriented therapies ...

Call: OPUS 20 , Panel: NZ5

Principal investigator: dr Natalia Bednarz-Knoll

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

Call: MAESTRO 12 , Panel: NZ3

Principal investigator: prof. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Modulation of immune cells activity in the tumor microenvironment by oligonucleotide therapeutics delivered by silk nano...

Call: OPUS 19 , Panel: NZ6

Principal investigator: prof. Hanna Dams-Kozłowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Atopic Dermatitis - searching for new strategic points of treatment, by evaluating clinical and prognostic significance ...

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Anna Maria Zaryczańska

Gdański Uniwersytet Medyczny, Wydział Lekarski

New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Anna Marta Pasieka

Uniwersytet Jagielloński, Collegium Medicum

Understanding of the mesenchymal stem cells (MSCs)-mediated immune suppression mechanism in the neutrophilic experimenta...

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: dr Marlena Tynecka

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

New insights into multifaceted targeted therapy for treatment of glioblastoma multiforme.

Call: OPUS 18 , Panel: NZ5

Principal investigator: dr Katarzyna Anna Malarz

Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

Call: OPUS 18 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The 'omics' of renal cancer nucleolus: towards identification of new cancer markers and therapeutic targets.

Call: OPUS 18 , Panel: NZ5

Principal investigator: prof. Agnieszka Piekiełko-Witkowska

Centrum Medyczne Kształcenia Podyplomowego, Szkoła Nauk Medycznych

Concomitant IDentification and Antibiotic REsistance profile of bacteria in one hour with an adaptive targeted single Ma...

Call: CHIST-ERA2018 , Panel: NZ6

Principal investigator: prof. Marek Tomasz Gniadkowski

Narodowy Instytut Leków