Projects funded by the NCN

An effect of lipid metabolism changes on the function of skeletal and heart muscles and neurodegeneration process in mou...

Call: PRELUDIUM 9 , Panel: NZ4

Principal investigator: Marta Urszula Tomczyk

Gdański Uniwersytet Medyczny, Wydział Lekarski

Comprehensive analysis of the therapeutic potential of oligonucleotides for the treatment of polyglutamine diseases

Call: SONATA 9 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Fiszer

Instytut Chemii Bioorganicznej PAN

Role of CacyBP/SIP in the dysregulation of beta-catenin ubiquitination in YAC128 mouse model of Huntington's disease

Call: SONATA 8 , Panel: NZ3

Principal investigator: dr Magdalena Czeredys

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

VDAC channel as a target of huntingtin in the etiology of Huntington's disease

Call: OPUS 1 , Panel: NZ3

Principal investigator: prof. Hanna Małgorzata Kmita

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The role of mitochondrial DNA and epigenetic factors in the pathogenesis of Huntington's disease

Call: OPUS 2 , Panel: NZ2

Principal investigator: prof. Janusz Limon

Gdański Uniwersytet Medyczny, Wydział Lekarski

Molecular insights into NAD+ metabolism in Huntington's disease: role in pathophysiology and preclinical assessment of t...

Call: OPUS 28 , Panel: NZ5

Principal investigator: dr hab. Marta Urszula Tomczyk

Gdański Uniwersytet Medyczny

Human iPSC-derived cortico-striatal assembloids as a new model to studyneurodevelopmental pathologies induced by mutant ...

Call: OPUS 25 , Panel: NZ3

Principal investigator: dr Magdalena Czeredys

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Defining (sex and age) cell-specific epigenetic mechanisms underlying EnvironmentalEnrichment/Exercise as non-pharmacolo...

Call: JPND Call 2022 , Panel: NZ2

Principal investigator: dr hab. Bartosz Zbigniew Wilczyński

Uniwersytet Warszawski

Searching for new therapeutic targets in polyglutamine diseases

Call: OPUS 22 , Panel: NZ2

Principal investigator: prof. Marta Olejniczak

Instytut Chemii Bioorganicznej PAN

Identification of novel disease modifiers in Huntington's disease: neuro-glia interactions in the patient-derived multid...

Call: SONATA BIS 11 , Panel: NZ3

Principal investigator: dr Agnieszka Marta Krzyżosiak

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

The use of artificial miRNAs in the therapy of Huntington's Disease

Call: PRELUDIUM 20 , Panel: NZ1

Principal investigator: dr Anna Kotowska-Zimmer

Instytut Chemii Bioorganicznej PAN

Molecular mechanisms of genistein-mediated autophagy stimulation, and its cellular and physiological effects in Huntingt...

Call: OPUS 19 , Panel: NZ2

Principal investigator: prof. Grzegorz Władysław Węgrzyn

Uniwersytet Gdański, Wydział Biologii

Linking abnormal Ca2+ signaling and the unfolded protein response with Huntington's disease pathology in both YAC128 mou...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr Magdalena Czeredys

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Discovering disorders of brain development in Huntington disease as a consequence of putative total huntingtin deficienc...

Call: OPUS 16 , Panel: NZ3

Principal investigator: dr hab. Maciej Figiel

Instytut Chemii Bioorganicznej PAN

Role of arginase 2 in the function of the striatum and in the pathogenesis of Huntington's disease

Call: SONATA BIS 8 , Panel: NZ1

Principal investigator: dr Michał Tadeusz Węgrzynowicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Investigation of DNA double-strand break repair mechanisms in microsatellite regions using the CRISPR/Cas system

Call: OPUS 15 , Panel: NZ1

Principal investigator: dr hab. Marta Olejniczak

Instytut Chemii Bioorganicznej PAN

Modulation of mutant huntingtin level by genistein in the mouse model of Huntington's disease and its effects on psychom...

Call: PRELUDIUM 13 , Panel: NZ2

Principal investigator: Karolina Pierzynowska

Uniwersytet Gdański, Wydział Biologii

Changes in human skin cells mitochondria carrying mutations causing Huntington's diseasae

Call: PRELUDIUM 9 , Panel: NZ2

Principal investigator: Paulina Jędrak

Uniwersytet Gdański, Wydział Biologii

MicroRNA profiling in cellular models of Huntington's disease generated using iPSC technology

Call: PRELUDIUM 9 , Panel: NZ2

Principal investigator: dr Emilia Barbara Kozłowska

Instytut Chemii Bioorganicznej PAN