Projects funded by the NCN


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73 projects found matching your search criteria :

  1. Analysis of the inflammatory role of MCPIP2 using the CRISPR/dCas9-FokI system. Identification of MCPIP2 substrates and ...

    Call: OPUS 8 , Panel: NZ2

    Principal investigator: dr hab. Aneta Marzanna Kasza

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  2. Cooperation of PgFur with CRISPR-associated proteins and selected transcriptional regulatory factors in mechanisms of Po...

    Call: PRELUDIUM 8 , Panel: NZ6

    Principal investigator: Michał Sylwester Śmiga

    Uniwersytet Wrocławski, Wydział Biotechnologii

  3. Porphyromonas gingivalis: natural defense and regulatory mechanisms

    Call: SONATA 1 , Panel: NZ6

    Principal investigator: dr hab. Krzysztof Pyrć

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  4. Is ADP-ribosylation involved in the response to DNA double-strand breaks? An investigation employing the CRISPR-Cas9 sys...

    Call: PRELUDIUM 24 , Panel: NZ3

    Principal investigator: Weronika Justyna Pawluś

    Uniwersytet Jagielloński

  5. Advanced High-Throughput Microfluidic Platform for Engineered T-Cell Screening

    Call: SONATINA 9 , Panel: NZ7

    Principal investigator: dr Alicja Andrea Przybyszewska-Podstawka

    Uniwersytet Warszawski

  6. Regulatory Mechanisms of FtPLATZ3 and FtAThook Transcription Factors During Seed Development in Fagopyrum tataricum and ...

    Call: SHENG 4 , Panel: NZ9

    Principal investigator: dr hab. Alexander Betekhtin

    UNIWERSYTET ŚLĄSKI

  7. Reciprocal relationships in metastatic colorectal cancer and its niche – from adaptation to host organs to induced paren...

    Call: OPUS 28 (LAP) , Panel: NZ2

    Principal investigator: dr Michał Artur Bieńkowski

    Gdański Uniwersytet Medyczny

  8. Exploring DMRTA2 in Glioblastoma: Epigenetic Regulation, Angiogenesis Disruption, and Biomarker Development

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Marta Magdalena Maleszewska-Bobińska

    Uniwersytet Warszawski

  9. Decoding the molecular mechanisms behind indole-3-acetic acid's influence on liver cells

    Call: PRELUDIUM 23 , Panel: NZ2

    Principal investigator: Aleksandra Ewa Uryga

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  10. Novel effectors and terminators of CRISPR-Cas antiviral signaling

    Call: DAINA 3 , Panel: NZ1

    Principal investigator: prof. Matthias Bochtler

    Instytut Biochemii i Biofizyki PAN

  11. Miniature CRISPR/Cas nucleases for upregulation of utrophin expression: a novel approach for mutation-independent therap...

    Call: DAINA 3 , Panel: NZ3

    Principal investigator: prof. Józef Dulak

    Uniwersytet Jagielloński

  12. Interrogation of the antigen presentation dynamics via MHCII in tumor immune evasion through multimodal single-cell sequ...

    Call: SONATINA 8 , Panel: NZ2

    Principal investigator: dr Natalia Ochocka-Lewicka

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  13. Molecular mechanisms of plant response to Al stress.

    Call: OPUS 26 , Panel: NZ9

    Principal investigator: dr Miriam Ewa Szurman-Zubrzycka

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  14. Overcoming CAR-T cell exhaustion via CRISPR- based enhancer modification

    Call: PRELUDIUM 22 , Panel: NZ6

    Principal investigator: dr Karolina Rassek

    Instytut Genetyki Człowieka PAN

  15. Emerging reproductive technologies meet philosophy: the non-identity problem, harm, and counterfactuals

    Call: PRELUDIUM BIS 4 , Panel: HS1

    Principal investigator: dr hab. Tomasz Żuradzki

    Uniwersytet Jagielloński, Wydział Filozoficzny

  16. Unraveling genes and mechanisms underlying relapse of T-cell acute lymphoblastic leukemia

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Małgorzata Agnieszka Dawidowska

    Instytut Genetyki Człowieka PAN

  17. Bunyaviral strategies to reorganize and exploit cellular translation

    Call: SONATA BIS 12 , Panel: NZ1

    Principal investigator: dr Piotr Gerlach

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  18. Modifiers of Muscleblind-like genes expression in health and disease.

    Call: SONATA BIS 12 , Panel: NZ5

    Principal investigator: dr hab. Ewa Agnieszka Stępniak-Konieczna

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

  19. The role of lipoproteins and lipoprotein receptors in mediating the effects of childhood trauma on the brain and the ger...

    Call: PRELUDIUM 21 , Panel: NZ3

    Principal investigator: Weronika Tomaszewska

    Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

  20. Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii PAN

  21. Microscopic identification of proteins involved in DNA repair of CAG repeats regions

    Call: PRELUDIUM 21 , Panel: NZ3

    Principal investigator: Mateusz Przemysław Nowaczyk

    Instytut Chemii Bioorganicznej PAN

  22. Dysfunction of NFE2L1 and other family members causes damage in dopaminergic neuron function through dysregulated transc...

    Call: PRELUDIUM 21 , Panel: NZ5

    Principal investigator: Kamila Łuczyńska

    Instytut Genetyki i Hodowli Zwierząt PAN

  23. The role of MTARC2 protein-related metabolism changes in the intestinal tumorigenesis

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr hab. Michał Marek Mikula

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  24. Modulating effect of elicitors on the biosynthesis of bioactive metabolites in Nigella damascena in vitro cultures - A t...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Magdalena Klimek-Chodacka

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

  25. Investigation of Regenerative Effects of CRISPR/Cas9 Functionalized Piezoelectric Nerve Conduits on in vitro and in vivo...

    Call: M-ERA.NET3 Call 2021 , Panel: ST5

    Principal investigator: dr hab. Urszula Stachewicz

    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

  26. A new animal model of human McArdle disease in zebrafish (Danio rerio)

    Call: SONATA 17 , Panel: NZ4

    Principal investigator: dr Marta Migocka-Patrzałek

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  27. Searching for new therapeutic targets in polyglutamine diseases

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: prof. Marta Olejniczak

    Instytut Chemii Bioorganicznej PAN

  28. CRISPRi-based screening for Pseudomonas aeruginosa vulnerabilities to antibiotics

    Call: SONATA 17 , Panel: NZ2

    Principal investigator: dr Adam Kawałek

    Instytut Biochemii i Biofizyki PAN

  29. Evaluation of NOTCH1- and NOTCH3-dependent anticancer drug resistance in a 2D and 3D model of Head and Neck Squamous Cel...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: dr Joanna Elżbieta Kałafut

    Uniwersytet Medyczny w Lublinie

  30. Investigation of DNA repair mechanisms in DRPLA model using CRISPR-Cas system

    Call: PRELUDIUM 20 , Panel: NZ2

    Principal investigator: dr Magdalena Dąbrowska

    Instytut Chemii Bioorganicznej PAN

  31. Transcription factors as tools of massive operation in engineering of industrial traits in yeast

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr hab. Ewelina Celińska

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Nauk o Żywności i Żywieniu

  32. Chiroptical properties of proteins and their complexes (CRISPR/Cas-RNA), and their relationship to biological activity

    Call: SONATINA 5 , Panel: ST4

    Principal investigator: dr Monika Anna Hałat

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

  33. High throughput microfluidic system for fast determination of the equilibrium constant for biomolecular complexes: appli...

    Call: PRELUDIUM BIS 2 , Panel: ST4

    Principal investigator: prof. Robert Hołyst

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  34. Identification and characterization of genes and other molecular factors determinig grain size and weight in barley (Hor...

    Call: OPUS 20 , Panel: NZ9

    Principal investigator: dr Sebastian Gasparis

    Instytut Hodowli i Aklimatyzacji Roślin - Państwowy Instytut Badawczy

  35. Identification of surface proteins as alternate targets for CAR-T therapy against CD19-negative tumors.

    Call: PRELUDIUM BIS 2 , Panel: NZ6

    Principal investigator: dr hab. Magdalena Hanna Winiarska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  36. Targeted degradation of Rab geranylgeranyl transferase as a new approach to investigate prenylation of Rab GTPases

    Call: PRELUDIUM BIS 2 , Panel: NZ1

    Principal investigator: dr hab. Edyta Violetta Gendaszewska-Darmach

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  37. Genetic Analysis of the Formation of Fagopyrum Somatic Hybrids

    Call: SONATA BIS 10 , Panel: NZ9

    Principal investigator: dr Alexander Betekhtin

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  38. Comprehensive characteristics of the microenvironment of borderline, low-grade and high-grade serous ovarian tumors in t...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: dr Łukasz Michał Szafron

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  39. Understanding of human insulin maturation for cell and gene therapy in diabetes

    Call: OPUS 19 , Panel: NZ3

    Principal investigator: dr hab. Małgorzata Borowiak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  40. The cell reprogramming processes: epigenetic and proteomic analyses of the cell fate in common and Tartary buckwheat

    Call: OPUS 19 , Panel: NZ9

    Principal investigator: dr Alexander Betekhtin

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  41. Determination of the mechanisms responsible for the mobility of non-integrin laminin receptor (LamR) isoforms, including...

    Call: PRELUDIUM 19 , Panel: NZ1

    Principal investigator: Ewa Mazurkiewicz

    Uniwersytet Wrocławski, Wydział Biotechnologii

  42. The use of genome editing systems in experimental therapy of polyglutamine diseases

    Call: ETIUDA 8 , Panel: NZ2

    Principal investigator: Magdalena Dąbrowska

    Instytut Chemii Bioorganicznej PAN

  43. Reconstructing cardiovascular cell lineage evolution, one cell at a time

    Call: OPUS 18 , Panel: NZ2

    Principal investigator: dr hab. Cecilia Lanny Winata

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  44. Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Justyna Beata Barut

    Instytut Farmakologii PAN

  45. Gankyrin protein as a new potential therapeutic target in multiple myeloma

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr hab. Irena Misiewicz-Krzemińska

    Instytut Hematologii i Transfuzjologii

  46. Do the two barley genes HvGSK1.1 and HvGSK1.2 regulate salt tolerance and yield-related traits?

    Call: PRELUDIUM 17 , Panel: NZ9

    Principal investigator: dr Yuliya Kloc

    Instytut Hodowli i Aklimatyzacji Roślin - Państwowy Instytut Badawczy

  47. Using CRISPR/Cas9 genome editing to characterise candidate Clubroot resistance genes in Arabidopsis thaliana.

    Call: PRELUDIUM 17 , Panel: NZ9

    Principal investigator: Juan Camilo Ochoa Cabezas

    Instytut Genetyki Roślin PAN

  48. The role of utrophin in cardiomyopathy in Duchenne muscular dystrophy

    Call: PRELUDIUM 17 , Panel: NZ3

    Principal investigator: dr Kalina Andrysiak

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  49. Functional genomic analysis of Staphylococcus aureus Kayvirus genus phages in a search for molecular basis of wide host-...

    Call: OPUS 17 , Panel: NZ2

    Principal investigator: dr hab. Małgorzata Barbara Łobocka

    Instytut Biochemii i Biofizyki PAN

  50. Exploiting the natural variability to identify the key genes for building the broad and durable resistance to mite pests...

    Call: OPUS 17 , Panel: NZ9

    Principal investigator: prof. Marcin Krzysztof Filipecki

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii