Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Biological control and pharmacological regulation of RNAs implicated in aetiology of Parkinson's disease

2023/49/B/NZ1/02456

Keywords:

microRNAs RNA-binding proteins RNA-protein interactions miR-7 miR-153 HuR aplha-Synuclein Parkinson's disease

Descriptors:

  • NZ1_01:
  • NZ3_05:
  • NZ5_07:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Gracjan Patryk Michlewski 

Number of co-investigators in the project: 6

Call: OPUS 25 - announced on 2023-03-16

Amount awarded: 2 999 834 PLN

Project start date (Y-m-d): 2024-03-01

Project end date (Y-m-d): 2028-02-29

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Effects of genetic ablation and pharmacological inhibition of HuR on gene expression, iron metabolism, and hormone levels
    Authors:
    Nathalie Idlin, Sivakumar Krishnamoorthy, Magdalena Wolczyk, Mouad Fakhri, Michal Lechowski, Natalia Stec, Jacek Milek, Pratik Kumar Mandal, Jaroslaw Cendrowski, Christos Spanos, Magdalena Dziembowska, Katarzyna Mleczko-Sanecka, Juri Rappsilber & Gracjan Michlewski
    Academic press:
    BMC Biology (rok: 2025, tom: Jan 23; 23(1), strony: 45678), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12915-025-02131-z - link to the publication