Projects funded by the NCN
Coordination of the spliceosome expression-to-function during embryonic development
2022/46/E/NZ3/00141
Keywords:
embryonic stem cells splicing post-transcriptional regulation development cell differentiation
Descriptors:
- NZ3_008:
- NZ3_013:
- NZ1_001:
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: SONATA BIS 12 - announced on 2022-05-15
Amount awarded: 4 817 800 PLN
Project start date (Y-m-d): 2023-03-22
Project end date (Y-m-d): 2028-03-21
Project duration:: 60 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- G)Patching up mis-splicing in cancerAuthors:Maciej Cieśla, Cristian BellodiAcademic press:Trends in Biochemical Sciences (rok: 2024, tom: 49(7), strony: 564-566), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.tibs.2024.05.001 - link to the publication
- The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicingAuthors:Matheus H Dias, Vladyslava Liudkovska, Jasmine Montenegro Navarro, Lisanne Giebel, Julien Champagne, Chrysa Papagianni, Onno B Bleijerveld, Arno Velds, Reuven Agami, René Bernards, Maciej CieślaAcademic press:EMBO Reports (rok: 2024, tom: 25 (5), strony: 2220-2238), Wydawca: EMBOStatus:PublishedDOI:10.1038/s44319-024-00128-3 - link to the publication