Molecular biomechanics of the SARS-CoV-2 variants: The virus-host cell attachment and immune evasion
2022/45/B/NZ1/02519
Keywords
Descriptors
- NZ1_003: Biofizyka
- NZ2_008: Biologia obliczeniowa
- ST3_016: Fizyka układów biologicznych
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Instytut Podstawowych Problemów Techniki Polska Akademia Nauk
Voivodeship: mazowieckie
Principal investigator (from the host institution)
dr hab. Adolfo Maximo Poma Bernaola
Number of co-investigators in the project: 3
Call
OPUS 23 – announced on 2022-03-28
- Amount awarded
- 1 760 460 PLN
- Project start date
- 2023-01-03
- Project end date
- 2027-01-02
- Project duration
- 48 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (4)
-
Single-Molecule Investigation of the Binding Interface Stability of SARS-CoV-2 Variants with ACE2
- Authors:
- Ray A, Minh T.T. M, Natividade R.d.S., Moreira R.A., Simpson J.D., Mohammed D., Koehler M., Petitjean S.J.L, Zhang Q., Bureau F., Gillet L., Poma A.B, Alsteens D.
- Academic press:
- ACS Nanoscience Au (year: 2024, volume: 4, pages: 136-145), Publisher: ACS
- Status:
- Published
- DOI:
- 10.1021/acsnanoscienceau.3c00060 – link to the publication
-
The GōMartini Approach: Revisiting the Concept of Contact Maps and the Modelling of Protein Complexes
- Authors:
- L.F. Cofas-Vargas, R.A. Moreira, S. Poblete, M. Chwastyk, A.B. Poma
- Academic press:
- Acta Physica Polonica A (year: 2024, volume: 145, pages: 20), Publisher: Institute of Physics of the Polish Academy of Science
- Status:
- Published
- DOI:
- 10.12693/APhysPolA.145.S9 – link to the publication
-
Nanomechanical footprint of SARS-CoV-2 variants in complex with a potent nanobody by molecular simulations
- Authors:
- Cofas-Vargas L.F.,Olivos-Ramirez G.E., Chwastyk M., Moreira R.A.M., Baker J.L., Marrink S.J., Poma A.B.
- Academic press:
- Nanoscale (year: 2024, volume: 16, pages: 18824-18834), Publisher: Royal Society of Chemistry
- Status:
- Published
- DOI:
- 10.1039/D4NR02074J – link to the publication
-
Conformational and stability analysis of SARS-CoV-2 spike protein variants by molecular simulation
- Authors:
- Olivos-Ramirez G.E., Cofas-Vargas L.F., ,Madl T., Poma A.B
- Academic press:
- Pathogens (year: 2025, volume: 14, pages: 274), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/pathogens14030274 – link to the publication