Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Composition-to-function analysis of SF3 complex in hematopoietic stem cells

2021/43/B/NZ3/01177

Keywords:

hematopoietic stem cells splicing post-transcriptional regulation cell differentiation

Descriptors:

  • NZ3_008:
  • NZ1_001:
  • NZ3_002:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Maciej Andrzej Cieśla 

Number of co-investigators in the project: 4

Call: OPUS 22 - announced on 2021-09-15

Amount awarded: 2 997 100 PLN

Project start date (Y-m-d): 2022-06-07

Project end date (Y-m-d): 2026-06-06

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. (G)Patching up mis-splicing in cancer
    Authors:
    Maciej Cieśla, Cristian Bellodi
    Academic press:
    Trends in Biochemical Sciences (rok: 2024, tom: 49(7), strony: 564-566), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tibs.2024.05.001 - link to the publication
  2. The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing
    Authors:
    Matheus H Dias, Vladyslava Liudkovska, Jasmine Montenegro Navarro, Lisanne Giebel, Julien Champagne, Chrysa Papagianni, Onno B Bleijerveld, Arno Velds, Reuven Agami, René Bernards, Maciej Cieśla
    Academic press:
    EMBO Reports (rok: 2024, tom: 25 (5), strony: 2220-2238), Wydawca: EMBO
    Status:
    Published
    DOI:
    10.1038/s44319-024-00128-3 - link to the publication