Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Understanding the biophysical limiting factors of patterning precision in developing tissues

2021/42/E/NZ2/00188

Keywords:

patterning precision cell division tissue growth vertex models spinal cord development heart development

Descriptors:

  • NZ2_009:
  • NZ2_008:
  • ST2_017:

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marcin Paweł Zagórski 

Number of co-investigators in the project: 5

Call: SONATA BIS 11 - announced on 2021-06-15

Amount awarded: 3 246 460 PLN

Project start date (Y-m-d): 2022-07-01

Project end date (Y-m-d): 2028-06-30

Project duration:: 72 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Stable developmental patterns of gene expression without morphogen gradients
    Authors:
    M. Majka, N. B. Becker, P. R. ten Wolde, M. Zagorski, T. R. Sokolowski
    Academic press:
    PLOS Computational Biology (rok: 2024, tom: 20, strony: e1012555), Wydawca: Public Library of Science (PLoS)
    Status:
    Published
    DOI:
    10.1371/journal.pcbi.1012555 - link to the publication
  2. Dynamics of morphogen source formation in a growing tissue
    Authors:
    R.D.J.G. Ho, K. Kishi, M. Majka, A. Kicheva, M. Zagorski
    Academic press:
    PLOS Computational Biology (rok: 2024, tom: 20, strony: e1012508), Wydawca: Public Library of Science (PLoS)
    Status:
    Published
    DOI:
    10.1371/journal.pcbi.1012508 - link to the publication
  3. scRNA-seq reveals the diversity of the developing cardiac cell lineage and molecular players in heart rhythm regulation
    Authors:
    K. A. Nahia, A. Sulej, M. Migdał, N. Ochocka, R. Ho, B. Kamińska, M. Zagorski, C. L. Winata
    Academic press:
    iScience (rok: 2024, tom: 27, strony: 45678), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.isci.2024.110083 - link to the publication
  4. Assessing the precision of morphogen gradients in neural tube development
    Authors:
    M. Zagorski, Y. Tabata, N. Brandenberg, M. P. Lutolf, G. Tkačik, T. Bollenbach, J. Briscoe, A. Kicheva
    Academic press:
    Nature Communications (rok: 2024, tom: 15, strony: 929), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41467-024-45148-8 - link to the publication
  5. Assessing the precision of morphogen gradients in neural tube development
    Authors:
    M. Zagorski, Y. Tabata, N. Brandenberg, M. P. Lutolf, G. Tkačik, T. Bollenbach, J. Briscoe, A. Kicheva
    Academic press:
    Nature Communications (rok: 2024, tom: 15, strony: 929), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41467-024-45148-8 - link to the publication