Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Biotinylated boronic acid derivative as a tool for targetable detection of oxidants in cancer cells

2021/41/N/ST4/00616

Keywords:

styryl dyes oxidative stress boronate probes biological oxidants peroxynitrite hypochlorous acid hydrogen peroxide fluorescence imaging targetable probes cancer cells

Descriptors:

  • ST4_005:
  • ST4_021:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Politechnika Łódzka, Wydział Chemiczny

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Przemysław Adam Siarkiewicz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 20 - announced on 2021-03-15

Amount awarded: 139 934 PLN

Project start date (Y-m-d): 2022-01-12

Project end date (Y-m-d): 2024-07-11

Project duration:: 30 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Evaluation of a novel pyridinium cation-linked styryl-based boronate probe for the detection of selected inflammation-related oxidants
    Authors:
    Przemysław Siarkiewicz, Bogusława Luzak, Radosław Michalski, Angelika Artelska, Marcin Szala, Tomasz Przygodzki, Adam Sikora, Jacek Zielonka, Aleksandra Grzelakowska, Radosław Podsiadły
    Academic press:
    Free Radical Biology and Medicine (rok: 2023, tom: 212, strony: 255-270), Wydawca: Free Radical Biology and Medicine
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2023.12.003 - link to the publication