Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Impact of voluntary physical activity and exercise mimetics on the neuroinflammation-related changes induced by an estrogen deficiency in ovariectomized middle-aged mice

2021/41/N/NZ7/01581

Keywords:

physical activity exercise mimetics neuroinflammation menopause ovariectomy

Descriptors:

  • NZ7_012:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Konstancja Imogena Grabowska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 20 - announced on 2021-03-15

Amount awarded: 209 692 PLN

Project start date (Y-m-d): 2022-02-15

Project end date (Y-m-d): 2025-08-14

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Effects of voluntary wheel running on appetite-regulating peptides and neuroinflammation in the hypothalamus of ovariectomized middle-aged mice
    Authors:
    Mateusz Grabowski, Konstancja Grabowska, Magdalena Kostka, Natalia Pondel, Halina Jędrzejowska-Szypułka, Andrzej Małecki, Jarosław J Barski, Marta Maria Nowacka-Chmielewska
    Academic press:
    Frontiers in Molecular Neuroscience (rok: 2025, tom: 18:1698306, strony: 46038), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fnmol.2025.1698306 - link to the publication
  2. Age-dependent neuroinflammation response to voluntary wheel running and metformin treatment in the frontal cortex of ovariectomized female mice
    Authors:
    Konstancja Grabowska, Mateusz Grabowski, Julia Morys, Edyta Olakowska, Andrzej Małecki, Jarosław Barski, Marta Nowacka-Chmielewska
    Academic press:
    Scientific Reports (rok: 2025, tom: 15, strony: 46042), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-025-10014-0 - link to the publication