Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The role of ATP-dependent activation of P2 purinergic receptors in the energetic disturbances in the brain of autistic-like animals

2021/41/N/NZ4/02350

Keywords:

autism mitochondria dysfunction synaptosomes gliosomes purinergic signaling

Descriptors:

  • NZ4_009:
  • NZ4_011:
  • NZ3_007:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Lidia Maria Babiec 

Number of co-investigators in the project: 2

Call: PRELUDIUM 20 - announced on 2021-03-15

Amount awarded: 209 893 PLN

Project start date (Y-m-d): 2022-01-12

Project end date (Y-m-d): 2025-01-11

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Prenatal exposure to valproic acid induces alterations in the expression and activity of purinergic receptors in the embryonic rat brain.
    Authors:
    Lidia Babiec, Anna Wilkaniec, Agata Adamczyk
    Academic press:
    Folia Neuropathologica (rok: 2022, tom: 60 (4), strony: 390-402), Wydawca: Termedia Sp. z o.o.
    Status:
    Published
    DOI:
    10.5114/fn.2022.123999 - link to the publication
  2. Alterations of Purinergic Receptors Levels and Their Involvement in the Glial Cell Morphology in a Pre-Clinical Model of Autism Spectrum Disorders
    Authors:
    Lidia Babiec, Anna Wilkaniec, Marta Martuszewska, Ewelina Pałasz, Magdalena Cieślik, Agata Adamczyk
    Academic press:
    Brain Sciences (rok: 2023, tom: 13, strony: 1088), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/brainsci13071088 - link to the publication
  3. Prenatal exposure to valproic acid induces alterations in the expression and activity of purinergic receptors in the embryonic rat brain.
    Authors:
    Lidia Babiec, Anna Wilkaniec, Agata Adamczyk
    Academic press:
    Folia Neuropathologica (rok: 2022, tom: 60 (4), strony: 390-402), Wydawca: Termedia Sp. z o.o.
    Status:
    Published
    DOI:
    10.5114/fn.2022.123999 - link to the publication

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