Early and late consequences of stem cell compartment damage due to SARS-CoV-2 infection
2021/41/B/NZ6/01590
Keywords
Descriptors
- NZ6_001: Odporność swoista i nieswoista
- NZ6_002: Immunologia kliniczna
Panel
NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution
Warszawski Uniwersytet Medyczny
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 5
Call
OPUS 21 – announced on 2021-03-15
- Amount awarded
- 2 381 440 PLN
- Project start date
- 2022-01-21
- Project end date
- 2026-05-20
- Project duration
- 52 months (the same as in the proposal)
- Project status
- Project completed
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (6)
-
Proteomic Analysis of Murine Bone Marrow Very Small Embryonic-like Stem Cells at Steady-State Conditions and after In Vivo Stimulation by Nicotinamide and Follicle-Stimulating Factor Reflects their Germ-Lineage Origin and Multi Germ Layer Differentiation Potential
- Authors:
- Chumak V, Sielatycka K, Ciechanowicz A, Bujko K, Ratajczak MZ, Kucia M.
- Academic press:
- Stem Cell Reviews and Reports (year: 2022, volume: 1, pages: 120-132), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s12015-022-10445-6 – link to the publication
-
Very small embryonic-like stem cells (VSELs) on the way for potential applications in regenerative medicine
- Authors:
- Thetchinamoorthy, K., Jarczak, J., Kieszek, P., Wierzbicka, D., Ratajczak, J., Kucia, M., & Ratajczak, M. Z.
- Academic press:
- Frontiers in bioengineering and biotechnology (year: 2025, volume: 13, pages: 1564964), Publisher: Frontiers
- Status:
- Published
- DOI:
- 10.3389/fbioe.2025.1564964 – link to the publication
-
Next-generation sequencing protocol of hematopoietic stem cells (HSCs). Step-by-step overview and troubleshooting guide.
- Authors:
- Jarczak, J., Bujko, K., Brzeźniakiewicz-Janus, K., Ratajczak, M., & Kucia, M.
- Academic press:
- PloS one (year: 2025, volume: 1, pages: 46035), Publisher: PLOS
- Status:
- Published
- DOI:
- 10.1371/journal.pone.0313009 – link to the publication
-
Human CD34+ very small embryonic-like stem cells can give rise to endothelial colony-forming cells with a multistep differentiation strategy using UM171 and nicotinamide acid.
- Authors:
- Domingues A, Rossi E, Bujko K, Detriche G, Richez U, Blandinieres A, Kucia M, Ratajczak J, Smadja DM, Ratajczak MZ.
- Academic press:
- Leukemia (year: 2022, volume: 5, pages: 1440-1443), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1038/s41375-022-01517-0 – link to the publication
-
scRNA-seq revealed transcriptional signatures of human umbilical cord primitive stem cells and their germ lineage origin regulated by imprinted genes.
- Authors:
- Jarczak, J., Bujko, K., Ratajczak, M. Z., & Kucia, M.
- Academic press:
- Scientific reports (year: 2024, volume: 14, pages: 29264), Publisher: Nature Portfolio
- Status:
- Published
- DOI:
- 10.1038/s41598-024-79810-4 – link to the publication
-
Angiotensin 1-7 Stimulates Proliferation of Lung Bronchoalveolar Progenitors-Implications for SARS-CoV-2 Infection
- Authors:
- Ciechanowicz AK, Lay WX, Prado Paulino J, Suchocki E, Leszczak S, Leszczak C, Kucia M.
- Academic press:
- Cells (year: 2022, volume: 13, pages: 46037), Publisher: mdpi
- Status:
- Published
- DOI:
- 10.3390/cells11132102 – link to the publication