The interactome of Upf1 (Nam7) ubiquitin ligase - deciphering thesubstrates and novel biological functions

2021/41/N/NZ2/00551

Keywords

Descriptors

  • NZ2_003: Proteomika
  • NZ2_009: Biologia systemowa
  • NZ3_001: Biologia komórki

Panel

NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Natalia Joanna Łazarewicz

Number of co-investigators in the project: 2

Call

PRELUDIUM 20 – announced on 2021-03-15

Amount awarded
139 000 PLN
Project start date
2022-01-13
Project end date
2025-01-12
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. UPF1—From mRNA Degradation to Human Disorders

    Authors:
    Jacek Staszewski, Natalia Łazarewicz, Julia Kończak, Iwona Migdał, Ewa Maciaszczyk-Dziubinska
    Academic press:
    Cells (year: 2023, volume: 12, pages: 46047), Publisher: Mdpi
    Status:
    Published
    DOI:
    10.3390/cells12030419 – link to the publication
  2. Multilevel Regulation of Membrane Proteins in Response to Metal and Metalloid Stress: A Lesson from Yeast

    Authors:
    Kacper Zbieralski , Jacek Staszewski , Julia Konczak , Natalia Lazarewicz , Malgorzata Nowicka-Kazmierczak , Donata Wawrzycka, Ewa Maciaszczyk-Dziubinska
    Academic press:
    International Journal of Molecular Sciences (year: 2024, volume: 25, pages: 46052), Publisher: Mdpi
    Status:
    Published
    DOI:
    10.3390/ijms25084450 – link to the publication
  3. Accurate and sensitive interactome profiling using a quantitative protein-fragment complementation assay

    Authors:
    Natalia Lazarewicz, Gaelle Le Dez, Romina Cerjani, Lunelys Runeshaw, Matthias Meurer, Michael Knop, Robert Wysocki, Gwenael Rabut
    Academic press:
    Cell Reports: Methods (year: 2024, volume: 4, pages: 46034), Publisher: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.crmeth.2024.100880 – link to the publication

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Graphic design and implementation: Jakub Piotrowski