Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The isolation of phenolic components of Zingiber officinale extracts and the assessment of their anticonvulsant activity in in vivo models

2021/41/B/NZ4/00337

Keywords:

Zingiber officinale chromatography epilepsy Danio rerio larvae mice models of seizures/epilepsy EEG anticonvulsant/antiepileptic activity locomotor activity anxiety-like behavior depressive-like behavior qRT-PCR

Descriptors:

  • ST4_005:
  • NZ7_012:
  • NZ4_009:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Wirginia Anna Kukuła-Koch 

Number of co-investigators in the project: 6

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 2 534 795 PLN

Project start date (Y-m-d): 2022-03-01

Project end date (Y-m-d): 2026-02-28

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (11)
  1. Zingiber officinale Rosc. in the Treatment of Metabolic Syndrome Disorders—A Review of In Vivo Studies
    Authors:
    Ewelina Gumbarewicz, Agata Jarzab, Andrzej Stepulak and Wirginia Kukula-Koch
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(24), strony: 15545), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms232415545 - link to the publication
  2. Zingiber officinale Rosc. in the Treatment of Metabolic Syndrome Disorders—A Review of In Vivo Studies
    Authors:
    Ewelina Gumbarewicz, Agata Jarzab, Andrzej Stepulak and Wirginia Kukula-Koch
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(24), strony: 15545), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms232415545 - link to the publication
  3. Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties—a review
    Authors:
    Bartosz Knap, Dorota Nieoczym, Uday Kundap, Kamila Kusio-Targonska, Wirginia Kukula-Koch, Waldemar A. Turski, Kinga Gawel
    Academic press:
    Frontiers in Molecular Neuroscience (rok: 2023, tom: 16, strony: 1221665), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnmol.2023.1221665 - link to the publication
  4. Impact of Thermal Processing on the Composition of Secondary Metabolites of Ginger Rhizome—A Review
    Authors:
    Justyna Zagórska, Lidia Czernicka-Bos, Wirginia Kukula-Koch, Radosław Szalak, Wojciech Koch
    Academic press:
    Foods (rok: 2022, tom: 11, strony: 3484), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  5. Impact of Thermal Processing on the Composition of Secondary Metabolites of Ginger Rhizome—A Review
    Authors:
    Justyna Zagórska, Lidia Czernicka-Bos, Wirginia Kukula-Koch, Radosław Szalak, Wojciech Koch
    Academic press:
    Foods (rok: 2022, tom: 11, strony: 3484), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  6. Impact of Thermal Processing on the Selected Biological Activities of Ginger Rhizome—A Review
    Authors:
    Justyna Zagórska, Lidia Czernicka-Boś, Wirginia Kukula-Koch, Katarzyna Iłowiecka, Wojciech Koch
    Academic press:
    Molecules (rok: 2022, tom: 28(1), strony: 412), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules28010412 - link to the publication
  7. Impact of Thermal Processing on the Selected Biological Activities of Ginger Rhizome—A Review
    Authors:
    Justyna Zagórska, Lidia Czernicka-Boś, Wirginia Kukula-Koch, Katarzyna Iłowiecka, Wojciech Koch
    Academic press:
    Molecules (rok: 2022, tom: 28(1), strony: 412), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules28010412 - link to the publication
  8. Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties—a review
    Authors:
    Bartosz Knap, Dorota Nieoczym, Uday Kundap, Kamila Kusio-Targonska, Wirginia Kukula-Koch, Waldemar A. Turski, Kinga Gawel
    Academic press:
    Frontiers in Molecular Neuroscience (rok: 2023, tom: 16, strony: 1221665), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnmol.2023.1221665 - link to the publication
  9. Impact of Thermal Processing on the Composition of Secondary Metabolites of Ginger Rhizome—A Review
    Authors:
    Justyna Zagórska, Lidia Czernicka-Bos, Wirginia Kukula-Koch, Radosław Szalak, Wojciech Koch
    Academic press:
    Foods (rok: 2022, tom: 11, strony: 3484), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  10. Impact of Thermal Processing on the Selected Biological Activities of Ginger Rhizome—A Review
    Authors:
    Justyna Zagórska, Lidia Czernicka-Boś, Wirginia Kukula-Koch, Katarzyna Iłowiecka, Wojciech Koch
    Academic press:
    Molecules (rok: 2022, tom: 28(1), strony: 412), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules28010412 - link to the publication
  11. Zingiber officinale Rosc. in the Treatment of Metabolic Syndrome Disorders—A Review of In Vivo Studies
    Authors:
    Ewelina Gumbarewicz, Agata Jarzab, Andrzej Stepulak and Wirginia Kukula-Koch
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(24), strony: 15545), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms232415545 - link to the publication

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