Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Cooperative and collective phenomena in cell membrane adhesion

2021/40/Q/NZ1/00017

Keywords:

cell membranes membrane receptors adhesion cooperative binding lipid rafts computer simulations molecular biophysics

Descriptors:

  • NZ1_003:
  • ST4_004:
  • ST3_016:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Fizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Bartosz Jan Różycki 

Number of co-investigators in the project: 2

Call: SHENG 2 - announced on 2020-12-15

Amount awarded: 395 280 PLN

Project start date (Y-m-d): 2022-03-01

Project end date (Y-m-d): 2026-02-28

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Book publications / chapters in book publications (2)
  1. Mechanical forces impair antigen discrimination by reducing differences in T-cell receptor/peptide–MHC off-rates
    Authors:
    Johannes Pettmann, Lama Awada, Bartosz Różycki, Anna Huhn, Sara Faour, Mikhail Kutuzov, Laurent Limozin, Thomas R. Weikl, P. Anton van der Merwe, Philippe Robert, Omer Dushek
    Academic press:
    EMBO Journal (rok: 2023, tom: 42, strony: e111841), Wydawca: EMBO Press
    Status:
    Published
    DOI:
    10.15252/embj.2022111841 - link to the publication
  2. Membrane-mediated cooperative interactions of CD47 and SIRPα
    Authors:
    Long Li, Chen Gui, Jinglei Hu, Bartosz Różycki
    Academic press:
    Membranes (rok: 2023, tom: 13, strony: 871), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/membranes13110871 - link to the publication
  3. Control of cell membrane receptor condensation by adhesion to supported bilayers with nanoscale topography
    Authors:
    Long Li, Ruihan Hou, Xinghua Shi, Jing Ji, Bartosz Różycki, Jinglei Hu, Fan Song
    Academic press:
    Communications Physics (rok: 2024, tom: 7, strony: 174), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s42005-024-01670-1 - link to the publication
  4. Interplay of receptor-ligand binding and lipid domain formation during cell adhesion
    Authors:
    Long Li, Jinglei Hu, Bartosz Różycki, Jing Ji, Fan Song
    Academic press:
    Frontiers in Molecular Biosciences (rok: 2022, tom: 9, strony: 1019477), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fmolb.2022.1019477 - link to the publication
  1. Lattice-based mesoscale simulations and mean-field theory of cell membrane adhesion
    Authors:
    Long Li, Jie Gao, Łukasz Milewski, Jinglei Hu, Bartosz Różycki
    Book:
    Methods in Enzymology (rok: 2024, tom: 701, strony: 425-455), Wydawca: Academic Press
    Status:
    Published
    DOI:
    10.1016/bs.mie.2024.03.005 - link to the publication
  2. Molecular Dynamics Simulations of Immune Receptors and Ligands
    Authors:
    Prithvi R. Pandey, Bartosz Różycki, Thomas R. Weikl
    Book:
    The Immune Synapse (rok: 2023, tom: 2654, strony: 51-59), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/978-1-0716-3135-5_4 - link to the publication

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