Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Does tormentil tincture (Tormentillae tinctura) support the therapy of leaky gut syndrome?

2021/40/C/NZ7/00231

Keywords:

leaky gut syndrome gut metabolism anti-diarrheal activity tormentil Tormentillae rhizoma

Descriptors:

  • NZ7_014:
  • NZ7_012:
  • NZ7_016:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Aleksandra Karolina Kruk 

Number of co-investigators in the project: 2

Call: SONATINA 5 - announced on 2020-12-15

Amount awarded: 862 808 PLN

Project start date (Y-m-d): 2021-11-02

Project end date (Y-m-d): 2025-11-01

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Heterogeneity of transport and metabolism of Tormentillae rhizoma constituents across human intestinal epithelium cellular model
    Authors:
    Aleksandra Kruk, Dominik Popowski, Marek Ł. Roszko, Sebastian Granica, Jakub P. Piwowarski
    Academic press:
    Food Research International (rok: 2024, tom: 188, strony: 45668), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.foodres.2024.114326 - link to the publication
  2. Selective metabolism of tormentil rhizome constituents by human gut microbiota and its impact on biodiversity ex vivo
    Authors:
    Aleksandra Kruk, Dominik Popowski, Paulina Średnicka, Marek Ł. Roszko, Sebastian Granica, Jakub P. Piwowarski
    Academic press:
    Food Chemistry (rok: 2025, tom: 478, strony: 45667), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.foodchem.2025.143674 - link to the publication