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The role of heat shock protein 90 in atopic dermatitis

2020/39/B/NZ6/00357

Keywords:

Atopic dermatitis heat shock proteins Hsp90

Descriptors:

  • NZ6_001:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Stefan Zbigniew Tukaj 

Number of co-investigators in the project: 2

Call: OPUS 20 - announced on 2020-09-15

Amount awarded: 1 022 800 PLN

Project start date (Y-m-d): 2021-06-11

Project end date (Y-m-d): 2025-06-10

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  1. Case Report: Circulating Anti-SARS-CoV-2 Antibodies Do Not Cross-React With Pemphigus or Pemphigoid Autoantigens
    Authors:
    Michael Kasperkiewicz, Marta Bednarek, Stefan Tukaj
    Academic press:
    Frontiers in Medicine , Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmed.2021.807711 - link to the publication
  2. Altered Gene Expression of IL-35 and IL-36α in the Skin of Patients with Atopic Dermatitis
    Authors:
    Weronika Zysk, Krzysztof Sitko, Stefan Tukaj, Anna Zaryczańska, Magdalena Trzeciak
    Academic press:
    Int J Mol Sci (tom: 25(1), strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25010404 - link to the publication
  3. Targeting heat shock proteins 90 and 70: A promising remedy for both autoimmune bullous diseases and COVID-19
    Authors:
    Michael Kasperkiewicz, Stefan Tukaj
    Academic press:
    Frontiers in Immunology , Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.1080786 - link to the publication
  4. Circulating heat shock protein 90 (Hsp90) in atopic dermatitis and bullous pemphigoid: is there a link?
    Authors:
    Stefan Tukaj
    Academic press:
    Cell Stress and Chaperones (), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12192-022-01298-6 - link to the publication
  5. Heat shock protein 90 (Hsp90) inhibitor STA-9090 (Ganetespib) ameliorates inflammation in a mouse model of atopic dermatitis
    Authors:
    Krzysztof Sitko, Michał Starke, Stefan Tukaj
    Academic press:
    Cell Stress Chaperones (tom: 28(6), strony: 935–942), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12192-023-01387-0 - link to the publication
  6. Circulating heat shock protein 90 (Hsp90) and autoantibodies to Hsp90 are increased in patients with atopic dermatitis
    Authors:
    Krzysztof Sitko, Marta Bednarek, Jagoda Mantej, Magdalena Trzeciak, Stefan Tukaj
    Academic press:
    Cell Stress and Chaperones (), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12192-021-01238-w - link to the publication
  7. Pathological Relevance of Anti-Hsp70 IgG Autoantibodies in Epidermolysis Bullosa Acquisita
    Authors:
    Stefan Tukaj, Jagoda Mantej, Krzysztof Sitko, Detlef Zillikens, Ralf J. Ludwig, Katja Bieber, Michael Kasperkiewicz
    Academic press:
    Frontiers in Immunology , Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.877958 - link to the publication
  8. Heat Shock Protein 90 (Hsp90) and Hsp70 as Potential Therapeutic Targets in Autoimmune Skin Diseases
    Authors:
    Stefan Tukaj, Krzysztof Sitko
    Academic press:
    Biomolecules , Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biom12081153 - link to the publication

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