Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Towards re-definition of the mechanisms of entotic cell death; the role of HAX1 and SEPT7 in the regulation of entosis in breast cancer models in vivo and in vitro.

2020/39/B/NZ3/03152

Keywords:

Entosis breast cancer HAX1 SEPT7 cell-cell adhesion

Descriptors:

  • NZ3_001:
  • NZ1_001:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Narodowy lnstytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy lnstytut Badawczy

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Anna Grzybowska 

Number of co-investigators in the project: 5

Call: OPUS 20 - announced on 2020-09-15

Amount awarded: 1 423 200 PLN

Project start date (Y-m-d): 2021-07-12

Project end date (Y-m-d): 2025-07-11

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. HAX1: A versatile, intrinsically disordered regulatory protein
    Authors:
    Alicja Trębińska-Stryjewska, Maciej Wakula, Mateusz Chmielarczyk, Ewa A Grzybowska
    Academic press:
    Biochim Biophys Acta Mol Cell Res . (rok: 2023, tom: Volume 1870, Issue 7, 119538, strony: -), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2023.119538 - link to the publication
  2. HAX1: A versatile, intrinsically disordered regulatory protein
    Authors:
    Alicja Trębińska-Stryjewska, Maciej Wakula, Mateusz Chmielarczyk, Ewa A Grzybowska
    Academic press:
    Biochim Biophys Acta Mol Cell Res . (rok: 2023, tom: Volume 1870, Issue 7, 119538, strony: -), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2023.119538 - link to the publication
  3. Cell Death by Entosis: Triggers, Molecular Mechanisms and Clinical Significance
    Authors:
    Mostafa Kianfar , Anna Balcerak , Mateusz Chmielarczyk , Leszek Tarnowski and Ewa A. Grzybowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(9), strony: 4985), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23094985 - link to the publication