Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Structure-function analysis of the catalytic center of the spliceosome

2020/39/B/NZ1/03273

Keywords:

spliceosome catalytic center snRNA catalysis

Descriptors:

  • NZ1_001:
  • NZ1_005:
  • NZ1_004:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Maria Magdalena Konarska 

Number of co-investigators in the project: 6

Call: OPUS 20 - announced on 2020-09-15

Amount awarded: 2 858 420 PLN

Project start date (Y-m-d): 2021-09-01

Project end date (Y-m-d): 2025-08-31

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Characterization of Cwc2, U6 snRNA, and Prp8 interactions destabilized by Prp16 ATPase at the transition between the first and second steps of splicing.
    Authors:
    Meissner, J., Eysmont, K., Matylla-Kulińska, K., & Konarska, M. M.
    Academic press:
    RNA (New York, N.Y.) (rok: 2024, tom: 30(9), strony: 1199–1212), Wydawca: CSHL Press
    Status:
    Published
    DOI:
    10.1261/rna.079886.123 - link to the publication