Conformational dynamics of Rad50 hook domain under controlled Zn(II) level

2020/37/N/NZ1/03319

Keywords

Descriptors

  • NZ1_003: Biofizyka
  • ST4_009: Chemia biologiczna
  • ST4_002: Metody spektroskopowe i spektrometryczne

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet Wrocławski, Wydział Biotechnologii

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Olga Dagmara Kerber

Number of co-investigators in the project: 2

Call

PRELUDIUM 19 – announced on 2020-03-16

Amount awarded
140 000 PLN
Project start date
2021-01-26
Project end date
2024-01-25
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (1)

  1. Zn(II) to Ag(I) Swap in Rad50 Zinc Hook Domain Leads to Interprotein Complex Disruption through the Formation of Highly Stable Agx(Cys)y Cores

    Authors:
    Olga Kerber, Józef Tran, Alicja Misiaszek, Aleksandra Chorążewska, Wojciech Bal, Artur Krężel
    Academic press:
    Inorganic Chemistry (year: 2023, volume: -, pages: -), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.inorgchem.2c03767 – link to the publication

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