Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Conformational dynamics of Rad50 hook domain under controlled Zn(II) level

2020/37/N/NZ1/03319

Keywords:

metalloproteins zinc hook Rad50

Descriptors:

  • NZ1_003:
  • ST4_009:
  • ST4_002:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Wrocławski, Wydział Biotechnologii

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Olga Dagmara Kerber 

Number of co-investigators in the project: 2

Call: PRELUDIUM 19 - announced on 2020-03-16

Amount awarded: 140 000 PLN

Project start date (Y-m-d): 2021-01-26

Project end date (Y-m-d): 2024-01-25

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Zn(II) to Ag(I) Swap in Rad50 Zinc Hook Domain Leads to Interprotein Complex Disruption through the Formation of Highly Stable Agx(Cys)y Cores
    Authors:
    Olga Kerber, Józef Tran, Alicja Misiaszek, Aleksandra Chorążewska, Wojciech Bal, Artur Krężel
    Academic press:
    Inorganic Chemistry (rok: 2023, tom: -, strony: -), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.inorgchem.2c03767 - link to the publication