Rac1 contribution to brain connectivity impairments and neuropsychiatric disorders in Tuberous Sclerosis Complex.

2020/37/B/NZ3/02345

Keywords

Descriptors

  • NZ3_006: Neurobiologia komórkowa
  • NZ3_005: Neurobiologia molekularna
  • NZ3_013: Biologia rozwoju zwierząt

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Justyna Zmorzyńska

Number of co-investigators in the project: 3

Call

OPUS 19 – announced on 2020-03-16

Amount awarded
2 251 260 PLN
Project start date
2021-01-04
Project end date
2025-07-03
Project duration
54 months (the same as in the proposal)
Project status
Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

  1. Hyperactive mTORC1 disrupts habenula function and light preference in zebrafish model of Tuberous sclerosis complex.

    Authors:
    O Doszyn, M Kedra, J Zmorzynska.
    Academic press:
    iScience (year: 2024, volume: 27(6), pages: 46034), Publisher: Cell Press / Elsevier
    Status:
    Published
    DOI:
    10.1016/j.isci.2024.110149 – link to the publication
  2. Diving into the zebrafish brain: exploring neuroscience frontiers with genetic tools, imaging techniques, and behavioral insights.

    Authors:
    O Doszyn*, T Dulski*, J Zmorzynska
    Academic press:
    Frontiers in Molecular Neuroscience (year: 2024, volume: 17, pages: 46040), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnmol.2024.1358844 – link to the publication

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