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Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Deciding the cell fate during UPR - are we barking up the wrong tree?

2020/37/B/NZ3/00861

Keywords:

microRNA UPR unfolded protein response ER stress

Descriptors:

  • NZ3_001:
  • NZ1_001:
  • NZ1_002:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Wrocławski, Wydział Biotechnologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Rafał Artur Bartoszewski 

Number of co-investigators in the project: 4

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 2 522 400 PLN

Project start date (Y-m-d): 2021-02-01

Project end date (Y-m-d): 2027-03-31

Project duration:: 74 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (14)
  1. Dual RNase activity of IRE1 as a target for anticancer therapies
    Authors:
    Sylwia Bartoszewska, Jakub Sławski, James F Collawn, Rafał Bartoszewski
    Academic press:
    Journal of Cell Communication and Signaling (rok: 2023, tom: 17, strony: 1145-1161), Wydawca: Springer Netherlands
    Status:
    Published
    DOI:
    10.1007/s12079-023-00784-5 - link to the publication
  2. Dual RNase activity of IRE1 as a target for anticancer therapies
    Authors:
    Sylwia Bartoszewska, Jakub Sławski, James F Collawn, Rafał Bartoszewski
    Academic press:
    Journal of Cell Communication and Signaling (rok: 2023, tom: 17, strony: 1145-1161), Wydawca: Springer Netherlands
    Status:
    Published
    DOI:
    10.1007/s12079-023-00784-5 - link to the publication
  3. Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor
    Authors:
    Magdalena Gebert, Aleksandra Sobolewska, Sylwia Bartoszewska, Aleksandra Cabaj, David K Crossman, Jaroslaw Kroliczewski, Piotr Madanecki, Michal Dabrowski, James F Collawn, Rafal Bartoszewski
    Academic press:
    Cellular and Molecular Life Sciences (rok: 2021, tom: 78, strony: 7061–7080), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-021-03952-1 - link to the publication
  4. 3. The Role of the Hypoxia-Related Unfolded Protein Response (UPR) in the Tumor Microenvironment
    Authors:
    Sylwia Bartoszewska , James F. Collawn and Rafal Bartoszewski
    Academic press:
    Cancers (rok: 2022, tom: 14(19), strony: 4870), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/cancers14194870 - link to the publication
  5. The Unfolded Protein Response: A Double-Edged Sword for Brain Health
    Authors:
    Magdalena Gebert, Jakub Sławski, Leszek Kalinowski, James F Collawn, Rafal Bartoszewski
    Academic press:
    Antioxidants (rok: 2023, tom: 12, strony: 1648), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/antiox12081648 - link to the publication
  6. Tytuł IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A
    Authors:
    Magdalena Gebert, Sylwia Bartoszewska, Lukasz Opalinski, James F Collawn, Rafał Bartoszewski
    Academic press:
    Cell Communication and Signaling (rok: 2023, tom: 21, strony: 322), Wydawca: Springer Netherlands
    Status:
    Published
    DOI:
    10.1186/s12964-023-01349-0 - link to the publication
  7. Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor
    Authors:
    Magdalena Gebert, Aleksandra Sobolewska, Sylwia Bartoszewska, Aleksandra Cabaj, David K Crossman, Jaroslaw Kroliczewski, Piotr Madanecki, Michal Dabrowski, James F Collawn, Rafal Bartoszewski
    Academic press:
    Cellular and Molecular Life Sciences (rok: 2021, tom: 78, strony: 7061–7080), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-021-03952-1 - link to the publication
  8. Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor
    Authors:
    Magdalena Gebert, Aleksandra Sobolewska, Sylwia Bartoszewska, Aleksandra Cabaj, David K Crossman, Jaroslaw Kroliczewski, Piotr Madanecki, Michal Dabrowski, James F Collawn, Rafal Bartoszewski
    Academic press:
    Cellular and Molecular Life Sciences (rok: 2021, tom: 78, strony: 7061–7080), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-021-03952-1 - link to the publication
  9. Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor
    Authors:
    Magdalena Gebert, Aleksandra Sobolewska, Sylwia Bartoszewska, Aleksandra Cabaj, David K Crossman, Jaroslaw Kroliczewski, Piotr Madanecki, Michal Dabrowski, James F Collawn, Rafal Bartoszewski
    Academic press:
    Cellular and Molecular Life Sciences (rok: 2021, tom: 78, strony: 7061–7080), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-021-03952-1 - link to the publication
  10. 3. The Role of the Hypoxia-Related Unfolded Protein Response (UPR) in the Tumor Microenvironment
    Authors:
    Sylwia Bartoszewska , James F. Collawn and Rafal Bartoszewski
    Academic press:
    Cancers (rok: 2022, tom: 14(19), strony: 4870), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/cancers14194870 - link to the publication
  11. The Unfolded Protein Response: A Double-Edged Sword for Brain Health
    Authors:
    Magdalena Gebert, Jakub Sławski, Leszek Kalinowski, James F Collawn, Rafal Bartoszewski
    Academic press:
    Antioxidants (rok: 2023, tom: 12, strony: 1648), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/antiox12081648 - link to the publication
  12. The Yin and Yang of hsa-miR-1244 expression levels during activation of the UPR control cell fate
    Authors:
    Paulina Czechowicz, Magdalena Gebert, Sylwia Bartoszewska, Leszek Kalinowski, James F Collawn, Rafal Bartoszewski
    Academic press:
    Cell Communication and Signaling (rok: 2024, tom: 22, strony: article number 577), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12964-024-01967-2 - link to the publication
  13. Tytuł IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A
    Authors:
    Magdalena Gebert, Sylwia Bartoszewska, Lukasz Opalinski, James F Collawn, Rafał Bartoszewski
    Academic press:
    Cell Communication and Signaling (rok: 2023, tom: 21, strony: 322), Wydawca: Springer Netherlands
    Status:
    Published
    DOI:
    10.1186/s12964-023-01349-0 - link to the publication
  14. 3. The Role of the Hypoxia-Related Unfolded Protein Response (UPR) in the Tumor Microenvironment
    Authors:
    Sylwia Bartoszewska , James F. Collawn and Rafal Bartoszewski
    Academic press:
    Cancers (rok: 2022, tom: 14(19), strony: 4870), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/cancers14194870 - link to the publication

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