Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Oxidative metabolism adaptation to Coenzyme Q deficiency in the brain; effect of statins

2020/37/B/NZ1/01188

Keywords:

statins brain mitochondria oxidative metabolism Coenzym Q

Descriptors:

  • NZ1_002:
  • NZ3_001:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Wiesława Jarmuszkiewicz 

Number of co-investigators in the project: 6

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 1 967 940 PLN

Project start date (Y-m-d): 2021-05-10

Project end date (Y-m-d): 2026-05-09

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (13)
  1. Carbon dioxide and MAPK signalling: towards therapy for inflammation
    Authors:
    Gałganska H, Jarmuszkiewicz W, Galganski L
    Academic press:
    Cell Communication and Signaling (rok: 2023, tom: 21, strony: 280), Wydawca: BioMed Central (BMC)
    Status:
    Published
    DOI:
    10.1186/s12964-023-01306-x - link to the publication
  2. Coenzyme Q deficiency in endothelial mitochondria caused by hypoxia; remodeling of the respiratory chain and sensitivity to anoxia/reoxygenation
    Authors:
    Karolina Dominiak, Lukasz Galganski, Adrianna Budzinska, Wieslawa Jarmuszkiewicz
    Academic press:
    Free Radical Biology Medicine (rok: 2024, tom: 214, strony: 158-170), Wydawca: Elsevier Inc
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2024.02.005 - link to the publication
  3. Mitochondrial coenzyme Q redox homeostasis and reactive oxygen species production
    Authors:
    Jarmuszkiewicz W, Dominiak K, Budzinska A, Wojcicki K, Galganski L
    Academic press:
    Frontiers in Bioscience (Landmark Ed) (rok: 2023, tom: 28(3), strony: 61), Wydawca: IMR Press
    Status:
    Published
    DOI:
    10.31083/j.fbl2803061 - link to the publication
  4. Endurance training increases the running performance of untrained men without changing the mitochondrial volume density in the gastrocnemius muscle
    Authors:
    Zoladz JA, Majerczak J, Galganski L, Grandys M, Zapart-Bukowska J, Kuczek P, Kołodziejski L, Walkowicz L, Szymoniak-Chochół D, Kilarski K, Jarmuszkiewicz W
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 1084), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms231810843 - link to the publication
  5. Effects of endurance training on the coenzyme Q redox state in rat heart, liver, and brain at the tissue and mitochondrial levels: implications for reactive oxygen species formation and respiratory chain remodeling
    Authors:
    Dominiak K, Galganski L, Budzinska A, Woyda-Ploszczyca A, Zoladz JA, Jarmuszkiewicz W
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(2), strony: 896), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23020896 - link to the publication
  6. Mitochondrial coenzyme Q redox homeostasis and reactive oxygen species production
    Authors:
    Jarmuszkiewicz W, Dominiak K, Budzinska A, Wojcicki K, Galganski L
    Academic press:
    Frontiers in Bioscience (Landmark Ed) (rok: 2023, tom: 28(3), strony: 61), Wydawca: IMR Press
    Status:
    Published
    DOI:
    10.31083/j.fbl2803061 - link to the publication
  7. Effects of atorvastatin and simvastatin on the bioenergetic function of isolated rat brain mitochondria
    Authors:
    Wojcicki K, Budzinska A, Jarmuszkiewicz W
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25(15), strony: 8494), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25158494 - link to the publication
  8. The bisphosphonates alendronate and zoledronate induce adaptations of aerobic metabolism in permanent human endothelial cells
    Authors:
    Budzinska A, Galganski L, Jarmuszkiewicz W
    Academic press:
    Scientific Reports (rok: 2023, tom: 13, strony: 16205), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-023-43377-3 - link to the publication
  9. Effects of endurance training on the coenzyme Q redox state in rat heart, liver, and brain at the tissue and mitochondrial levels: implications for reactive oxygen species formation and respiratory chain remodeling
    Authors:
    Dominiak K, Galganski L, Budzinska A, Woyda-Ploszczyca A, Zoladz JA, Jarmuszkiewicz W
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(2), strony: 896), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23020896 - link to the publication
  10. Endurance training increases the running performance of untrained men without changing the mitochondrial volume density in the gastrocnemius muscle
    Authors:
    Zoladz JA, Majerczak J, Galganski L, Grandys M, Zapart-Bukowska J, Kuczek P, Kołodziejski L, Walkowicz L, Szymoniak-Chochół D, Kilarski K, Jarmuszkiewicz W
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 1084), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms231810843 - link to the publication
  11. The bisphosphonates alendronate and zoledronate induce adaptations of aerobic metabolism in permanent human endothelial cells
    Authors:
    Budzinska A, Galganski L, Jarmuszkiewicz W
    Academic press:
    Scientific Reports (rok: 2023, tom: 13, strony: 16205), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-023-43377-3 - link to the publication
  12. Carbon dioxide and MAPK signalling: towards therapy for inflammation
    Authors:
    Gałganska H, Jarmuszkiewicz W, Galganski L
    Academic press:
    Cell Communication and Signaling (rok: 2023, tom: 21, strony: 280), Wydawca: BioMed Central (BMC)
    Status:
    Published
    DOI:
    10.1186/s12964-023-01306-x - link to the publication
  13. Effects of endurance training on the coenzyme Q redox state in rat heart, liver, and brain at the tissue and mitochondrial levels: implications for reactive oxygen species formation and respiratory chain remodeling
    Authors:
    Dominiak K, Galganski L, Budzinska A, Woyda-Ploszczyca A, Zoladz JA, Jarmuszkiewicz W
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(2), strony: 896), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23020896 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy