Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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VPS10P domain receptors in phenotypic polarization of astrocytes and microglia in the diseased brain.

2020/37/B/NZ3/00761

Keywords:

intracellular sorting cytokines extracellular matrix glia astrocytes microglia glioma transcription regulation expression control phenotypic polarization

Descriptors:

  • NZ3_006:
  • NZ3_005:
  • NZ3_001:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Warszawski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Róża Malik 

Number of co-investigators in the project: 4

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 2 206 536 PLN

Project start date (Y-m-d): 2021-07-30

Project end date (Y-m-d): 2026-07-29

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. SorLA restricts TNFα release from microglia to shape glioma-supportive brain microenvironment
    Authors:
    Paulina Kaminska, Peter L. Ovesen, Mateusz Jakiel, Tomasz Obrebski, Aleksandra Bilska,Vanessa Schmidt, Magdalena Bieniek, Jasper Anink, Bohdan Paterczyk, Michal Draminski, Anne Mette Gissel Jensen, Sylwia Piatek, Olav M. Andersen, Eleonora Aronica, Thomas E. Willnow, Bozena Kaminska, Michal J. Dabrowski, Anna R. Malik
    Academic press:
    EMBO Reports (rok: 2024, tom: 25, strony: 2278 - 2305), Wydawca: EMBO Press
    Status:
    Published
    DOI:
    10.1038/s44319-024-00117-6 - link to the publication
  2. SorLA restricts TNFα release from microglia to shape glioma-supportive brain microenvironment
    Authors:
    Paulina Kaminska, Peter L. Ovesen, Mateusz Jakiel, Tomasz Obrebski, Aleksandra Bilska,Vanessa Schmidt, Magdalena Bieniek, Jasper Anink, Bohdan Paterczyk, Michal Draminski, Anne Mette Gissel Jensen, Sylwia Piatek, Olav M. Andersen, Eleonora Aronica, Thomas E. Willnow, Bozena Kaminska, Michal J. Dabrowski, Anna R. Malik
    Academic press:
    EMBO Reports (rok: 2024, tom: 25, strony: 2278 - 2305), Wydawca: EMBO Press
    Status:
    Published
    DOI:
    10.1038/s44319-024-00117-6 - link to the publication
  3. Od laboratorium do kliniki: eksperymentalne modele zwierzęce w badaniach nad udarem niedokrwiennym mózgu
    Authors:
    Piątek S., Milewska P., Ziemlińska E, Malik AR
    Academic press:
    Postępy Biochemii (rok: 2024, tom: 70, strony: 497-507), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2021_570 - link to the publication
  4. Wszystko na swoim miejscu – rola receptorów VPS10P w komórkowej segregacji białek
    Authors:
    Kamińska P., Piątek S., Bieniek M., Malik AR
    Academic press:
    Postępy Biochemii (rok: 2023, tom: 69, strony: 26-41), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2021_473 - link to the publication
  5. Cytokines on the way to secretion
    Authors:
    Paulina Kaminska, Aleksandra Tempes, Ela Scholz, Anna R Malik
    Academic press:
    Cytokine & Growth Factor Reviews (rok: 2024, tom: 79, strony: 52-65), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cytogfr.2024.08.003 - link to the publication