Structural characterization of metallothionein zinc-loaded states and their role in regulation of p53 tumor supressor activity
2020/36/T/ST4/00404
Keywords
Descriptors
- ST4_009: Chemia biologiczna
- ST4_005: Chemia analityczna
- ST4_002: Metody spektroskopowe i spektrometryczne
Panel
ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution
Uniwersytet Wrocławski, Wydział Biotechnologii
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 1
Call
ETIUDA 8 – announced on 2019-12-16
- Amount awarded
- 130 104 PLN
- Project start date
- 2020-10-01
- Project end date
- 2021-09-30
- Project duration
- 12 months (the same as in the proposal)
- Project status
- Project completed
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
Structural Characterization of Cu(I)/Zn(II)-metallothionein-3 by Ion Mobility Mass Spectrometry and Top-Down Mass Spectrometry
- Authors:
- Manuel David Peris Diaz, Sylwia Wu, Karolina Mosna, Ellen Liggett, Alexey Barkhanskiy, Alicja Orzel, Perdita Barran, Artur Krężel
- Academic press:
- Analytical Chemistry (year: 2023, volume: 95, pages: 10966-10974), Publisher: American Chemical Society
- Status:
- Published
- DOI:
- 10.1021/acs.analchem.3c00989 – link to the publication
-
Ion mobility mass spectrometry and molecular dynamics simulations unravel the conformational stability and coordination dynamics of human metallothionein-2 species
- Authors:
- M. D. Peris-Díaz, A Barkhanskiy, E Liggett, P. Barran, A. Krężel
- Status:
- Accepted for publication