Structural characterization of metallothionein zinc-loaded states and their role in regulation of p53 tumor supressor activity

2020/36/T/ST4/00404

Keywords

Descriptors

  • ST4_009: Chemia biologiczna
  • ST4_005: Chemia analityczna
  • ST4_002: Metody spektroskopowe i spektrometryczne

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Wrocławski, Wydział Biotechnologii

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Manuel David Peris Diaz

Number of co-investigators in the project: 1

Call

ETIUDA 8 – announced on 2019-12-16

Amount awarded
130 104 PLN
Project start date
2020-10-01
Project end date
2021-09-30
Project duration
12 months (the same as in the proposal)
Project status
Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

  1. Structural Characterization of Cu(I)/Zn(II)-metallothionein-3 by Ion Mobility Mass Spectrometry and Top-Down Mass Spectrometry

    Authors:
    Manuel David Peris Diaz, Sylwia Wu, Karolina Mosna, Ellen Liggett, Alexey Barkhanskiy, Alicja Orzel, Perdita Barran, Artur Krężel
    Academic press:
    Analytical Chemistry (year: 2023, volume: 95, pages: 10966-10974), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.analchem.3c00989 – link to the publication
  2. Ion mobility mass spectrometry and molecular dynamics simulations unravel the conformational stability and coordination dynamics of human metallothionein-2 species

    Authors:
    M. D. Peris-Díaz, A Barkhanskiy, E Liggett, P. Barran, A. Krężel
    Status:
    Accepted for publication

« New search

Graphic design and implementation: Jakub Piotrowski