Cardioprotective flavonoids: new regulators of mitochondrial potassium channels?
2020/36/T/NZ1/00116
Keywords
Descriptors
- NZ1_003: Biofizyka
- NZ1_001: Biologia molekularna
- NZ1_002: Biochemia
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Instytut Biologii Doświadczalnej im. M. Nenckiego PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 1
Call
ETIUDA 8 – announced on 2019-12-16
- Amount awarded
- 138 168 PLN
- Project start date
- 2020-10-01
- Project end date
- 2022-07-01
- Project duration
- 22 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (5)
-
Cytoprotective effects of the flavonoid quercetin by activating mitochondrial BK Ca channels in endothelial cells
- Authors:
- Kampa RP, Sęk A, Szewczyk A, Bednarczyk P
- Academic press:
- Biomedicine & Pharacotherapy (year: 2021, volume: 142), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.biopha.2021.112039 – link to the publication
-
Flavonoids as new regulators of mitochondrial potassium channels: contribution to cardioprotection
- Authors:
- Kampa RP, Sęk A, Bednarczyk P, Szewczyk A, Calderone V, Testai L
- Academic press:
- Journal of Pharmacy and Pharmacology (year: 2023, volume: 75, pages: 466-481), Publisher: Oxford academic
- Status:
- Published
- DOI:
- 10.1093/jpp/rgac093 – link to the publication
-
Luteolin-induced activation of mitoBKCa channels: undisclosed mechanism of cardioprotection
- Authors:
- Kampa RP, Flori L, Sęk A, Spezzini J, Brogi S, Szewczyk A, Calderone V, Bednarczyk P, Testai L
- Academic press:
- Antioxidants (year: 2022, volume: 11, pages: 1892), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/antiox11101892 – link to the publication
-
Identification of the Large-Conductance Ca 2+-Regulated Potassium Channel in Mitochondria of Human Bronchial Epithelial Cells
- Authors:
- Sęk A, Kampa RP, Kulawiak B, Szewczyk A, Bednarczyk P
- Academic press:
- Molecules (year: 2021, volume: 26), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/molecules26113233 – link to the publication
-
Flavonoid quercetin abolish paxilline inhibition of the mitochondrial BKCa channel
- Authors:
- Kampa RP, Gliździńska A, Szewczyk A, Bednarczyk P, Filipek S
- Academic press:
- Mitochondrion (year: 2022, volume: 65, pages: 23-32), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.mito.2022.04.005 – link to the publication
Book publications / chapters in book publications (1)
-
Patch-Clamp Recording of the Activity of Ion Channels in the Inner Mitochondrial Membrane
- Authors:
- Bednarczyk P, Kampa RP, Gałecka S, Sęk A, Walewska A, Koprowski P
- Book:
- Mitochondrial Mdicine Volume 2: Assessing Mitochondria (year: 2021, pages: 235-248), Publisher: Springer Sciences + Business Media, LCC
- Status:
- Published
- DOI:
- 10.1007/978-1-0716-1266-8_18 – link to the publication