Trehalose releasing nanogels for autophagy stimulation

2019/35/O/ST5/02746

Keywords

Descriptors

  • ST5_010: Materiały /nanomateriały funkcjonalne, nanocząstki
  • ST5_005: Materiały polimerowe
  • ST4_008: Chemia organiczna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Politechnika Śląska, Wydział Chemiczny

Voivodeship: śląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Ilona Wioletta Wandzik

Number of co-investigators in the project: 2

Call

PRELUDIUM BIS 1 – announced on 2019-09-16

Amount awarded
532 800 PLN
Project start date
2020-10-01
Project end date
2024-09-30
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (5)

  1. A Simple Synthesis of Reduction-Responsive Acrylamide-Type Nanogels for miRNA Delivery

    Authors:
    Ali Maruf, Małgorzata Milewska, Anna Lalik, Sebastian Student, Ilona Wandzik
    Academic press:
    Molecules (year: 2023, volume: 28, pages: 761), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules28020761 – link to the publication
  2. pH and Reduction Dual-Responsive Nanogels as Smart Nanocarriers to Resist Doxorubicin Aggregation

    Authors:
    Ali Maruf, Małgorzata Milewska, Anna Lalik, Ilona Wandzik
    Academic press:
    Molecules (year: 2022, volume: 27, pages: 5983), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules27185983 – link to the publication
  3. Trehalose-releasing nanogels: A step toward a trehalose delivery vehicle for autophagy stimulation

    Authors:
    Ali Maruf, Małgorzata Milewska, Tibor Kovács, Máté Varga, Tibor Vellai, Anna Lalik, Sebastian Student, Olga Borges, Ilona Wandzik
    Academic press:
    Biomaterials Advances (wcześniej: Materials Science and Engineering C) (year: 2022, volume: 138, pages: 212969), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioadv.2022.212969 – link to the publication
  4. Trehalose-Bearing Carriers to Target Impaired Autophagy and Protein Aggregation Diseases

    Authors:
    Ali Maruf, Małgorzata Milewska, Mate Varga, Ilona Wandzik
    Academic press:
    Journal of Medicinal Chemistry (year: 2023, volume: 66, pages: 15613–15628), Publisher: ACS
    Status:
    Published
    DOI:
    10.1021/acs.jmedchem.3c01442 – link to the publication
  5. Nanogels with covalently bound and releasable trehalose for autophagy stimulation in atherosclerosis

    Authors:
    Yuan Zhong, Ali Maruf, Kai Qu, Małgorzata Milewska, Ilona Wandzik, Nianlian Mou, Yu Cao, Wei Wu
    Academic press:
    Journal of Nanobiotechnology (year: 2023, volume: 21, pages: 472), Publisher: BMC
    Status:
    Published
    DOI:
    10.1186/s12951-023-02248-9 – link to the publication

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Graphic design and implementation: Jakub Piotrowski