In search of spectroscopic markers of autophagy based on pharmacologically induced phospholipidosis in endothelial cells

2019/35/N/ST4/03896

Keywords

Descriptors

  • ST4_002: Metody spektroskopowe i spektrometryczne
  • NZ7_014: Farmacja, farmakoterapia, farmakologia
  • ST4_009: Chemia biologiczna

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Ewelina Joanna Bik

Number of co-investigators in the project: 2

Call

PRELUDIUM 18 – announced on 2019-09-16

Amount awarded
210 000 PLN
Project start date
2020-07-27
Project end date
2023-07-26
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

  1. Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium

    Authors:
    Ewelina Bik, Lukasz Mateuszuk, Jagoda Orleanska, Malgorzata Baranska, Stefan Chlopicki, Katarzyna Majzner
    Academic press:
    International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 2401), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22052401 – link to the publication
  2. Raman and fluorescence imaging of phospholipidosis induced by cationic amphiphilic drugs in endothelial cells

    Authors:
    Ewelina Bik, Jagoda Orleanska, Lukasz Mateuszuk, Malgorzata Baranska, Katarzyna Majzner, Stefan Chlopicki
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (year: 2022, volume: 1869, pages: 119186), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2021.119186 – link to the publication

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Graphic design and implementation: Jakub Piotrowski