Impact of indole-3-propionic acid, a gut microbiota-derived metabolite of tryptophan, on cardiovascular system in rats.
2019/35/N/NZ4/01111
Keywords
Descriptors
- NZ4_002: Fizjologia
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Warszawski Uniwersytet Medyczny
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 18 – announced on 2019-09-16
- Amount awarded
- 139 992 PLN
- Project start date
- 2020-06-25
- Project end date
- 2022-12-24
- Project duration
- 30 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
Indole-3-propionic acid, a tryptophan-derived bacterial metabolite, increases blood pressure via cardiac and vascular mechanisms in rats
- Authors:
- Piotr Konopelski, Dawid Chabowski, Marta Aleksandrowicz, Ewa Kozniewska, Piotr Podsadni, Agnieszka Szczepanska, Marcin Ufnal
- Academic press:
- American Journal of Physiology-Regulatory Integrative and Comparative Physiology (year: 2021, volume: 321, pages: R969-R981), Publisher: The American Physiological Society
- Status:
- Published
- DOI:
- 10.1152/ajpregu.00142.2021 – link to the publication
-
Biological Effects of Indole-3-Propionic Acid, a Gut Microbiota-Derived Metabolite, and Its Precursor Tryptophan in Mammals' Health and Disease
- Authors:
- Piotr Konopelski, Izabella Mogilnicka
- Academic press:
- International Journal of Molecular Sciences (year: 2022, volume: 23, pages: 46041), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms23031222 – link to the publication
Articles in post-conference publications (1)
-
Indole-3-propionic Acid, Bacterial Metabolite of Tryptophan, Increases Blood Pressure in Normotensive and Hypertensive Rats
- Authors:
- Piotr Konopelski, Dawid Chabowski, Marta Aleksandrowicz, Ewa Kozniewska, Piotr Podsadni, Agnieszka Szczepanska, Marcin Ufnal
- Conference:
- The FASEB Journal Volume 36, Issue S1 (year: 2022, volume: Experimental Biology 2022, pages: 1), Publisher: FASEB
- Date:
- conference 2-5 kwietnia 2022
- Status:
- Published
- DOI:
- 10.1096/fasebj.2022.36.S1.R3359 – link to the publication