Projects funded by the NCN
MOLECULAR INSIGHTS INTO BIOSYNTHESIS OF PEPTIDE AZOLE ANTIBIOTICS
2019/35/D/NZ1/01770
Keywords:
ribosomally synthesized post-translationally modified peptides cryo-electron microscopy x-ray crystallography antibiotics YcaO azole
Descriptors:
- NZ1_002:
- NZ1_004:
- NZ1_006:
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 4
Call: SONATA 15 - announced on 2019-09-16
Amount awarded: 1 480 092 PLN
Project start date (Y-m-d): 2020-06-29
Project end date (Y-m-d): 2021-11-28
Project duration:: 17 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Pentapeptide repeat protein QnrB1 requires ATP hydrolysis to rejuvenate poisoned gyrase complexesAuthors:Łukasz Mazurek, Dmitry Ghilarov, Elizabeth Michalczyk, Zuzanna Pakosz, Mikhail Metelev, Wojciech Czyszczoń, Karolina Wawro, Iraj Behroz, Svetlana Dubiley, Roderich D Süssmuth, Jonathan G HeddleAcademic press:Nucleic Acids Research (rok: 2021, tom: 49, strony: 1581–1596), Wydawca: Oxford AcademicStatus:PublishedDOI:10.1093/nar/gkaa1266 - link to the publication
- Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptidesAuthors:GHILAROV. D., INABA-INOUE, S., STEPIEN, P., QU, F., MICHALCZYK, E., PAKOSZ, Z., NOMURA, N., OGASAWARA, S., WALKER, G.C., REBUFFAT, S., IWATA, S., HEDDLE, J.G AND BEIS, K.Academic press:Science Advances (rok: 2021, tom: 7, strony: ), Wydawca: AAASStatus:PublishedDOI:10.1126/sciadv.abj5363 - link to the publication