Solid-state circular dichroism (CD) spectroscopies as a tool for supporting the

Solid-state circular dichroism (CD) spectroscopies as a tool for supporting the development of medicinal chemistry

2019/35/D/ST4/00394

Keywords

Descriptors

ST4_002: Metody spektroskopowe i spektrometryczne

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Instytut Chemii Organicznej Polska Akademia Nauk

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Marcin Janusz Górecki

Number of co-investigators in the project: 6

Call

SONATA 15 – announced on 2019-09-16

Amount awarded: 904 800 PLN
Project start date: 2020-09-01
Project end date: 2025-02-28
Project duration: 54 months (the same as in the proposal)
Project status: Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (5)

Enantioselective Gel Phase Synthesis of Metal–Organic Materials

Authors:
D. Ghosh, M. Górecki, G. Pescitelli, K. Kumar Damodaran

Academic press:
Angewandte Chemie - International Edition (year: 2021, volume: 60, pages: 24406–24410), Publisher: Wiley-VCH

Status:
Published

DOI:
10.1002/anie.202107040 – link to the publication
Towards seeking the right chiroptical tool to assign the stereochemistry of bioactive compounds: Effectiveness, challenges, and perspectives

Authors:
M. Górecki, J. Frelek

Academic press:
Trends in Analytical Chemistry (year: 2021, volume: 144, pages: 116428), Publisher: Elsevier

Status:
Published

DOI:
10.1016/j.trac.2021.116428 – link to the publication
Differentiation of solvatomorphs of active pharmaceutical ingredients (API) by solid-state vibrational circular dichroism (VCD)

Authors:
J. E. Rode, J. Wasilczenko, M. Górecki

Academic press:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (year: 2024, volume: 310, pages: 123851), Publisher: Elsevier

Status:
Published

DOI:
10.1016/j.saa.2024.123851 – link to the publication
A Holistic Approach to Determining Stereochemistry of Potential Pharmaceuticals by Circular Dichroism with β-Lactams as Test Cases

Authors:
M. Górecki, J. Frelek

Academic press:
International Journal of Molecular Sciences (year: 2021, volume: 23, pages: 273), Publisher: MDPI

Status:
Published

DOI:
10.3390/ijms23010273 – link to the publication
Electronic Circular Dichroism Imaging (CDi) casts a new light on the origin of solid-state chiroptical properties

Authors:
M. Górecki, F. Lipparini, G. Albano, T. Jávorfi, R. Hussain, G. Siligardi, G. Pescitelli, L. Di Bari

Academic press:
Chemistry - A European Journal (year: 2022, volume: 28, pages: e202103632), Publisher: Wiley-VCH

Status:
Published

DOI:
10.1002/chem.202103632 – link to the publication

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