Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The impact of cytoplasmic polyadenylation on local translation in neurons

2019/34/H/NZ3/00733

Keywords:

neurons polyadenylation local translation LTP TENT5 TENT2(GLD2) direct RNA sequencing

Descriptors:

  • NZ3_005:
  • NZ2_002:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Andrzej Stanisław Dziembowski 

Number of co-investigators in the project: 10

Call: GRIEG 1 - announced on 2019-06-17

Amount awarded: 6 380 050 PLN

Project start date (Y-m-d): 2020-09-01

Project end date (Y-m-d): 2024-04-30

Project duration:: 44 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. TENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice
    Authors:
    Michał Brouze, Agnieszka Czarnocka-Cieciura, Olga Gewartowska1,3,4, Monika Kusio-Kobiałka1 , Kamil Jachacy, Marcin Szpila, Bartosz Tarkowski, Jakub Gruchota, Paweł Krawczyk, Seweryn Mroczek, Ewa Borsuk & Andrzej Dziembowski
    Academic press:
    Nature Communications (rok: 2024, tom: XX, strony: 45677), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41467-024-49479-4 - link to the publication