Revealing sources of cell-to-cell heterogeneity in interferon gamma responses
2019/33/N/NZ2/02691
Keywords
Descriptors
- NZ2_009: Biologia systemowa
- NZ2_010: Modelowanie i symulacje biologiczne
- NZ3_007: Przekaźnictwo sygnału
Panel
NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology
Host institution
Instytut Podstawowych Problemów Techniki Polska Akademia Nauk
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 17 – announced on 2019-03-15
- Amount awarded
- 140 000 PLN
- Project start date
- 2020-02-05
- Project end date
- 2022-02-04
- Project duration
- 24 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
Phenotypic variability, not noise, accounts for most of the cell-to-cell heterogeneity in IFN-γ and oncostatin M signaling responses
- Authors:
- Topolewski, P., Zakrzewska, K.E., Walczak, J., Nienałtowski, K., Müller-Newen, G., Singh, A., Komorowski, M.
- Academic press:
- Science Signaling (year: 2022, volume: 15 (721), pages: eabd9303), Publisher: American Association for the Advancement of Science (AAAS)
- Status:
- Published
- DOI:
- 10.1126/scisignal.abd9303 – link to the publication
-
Information-theoretic analyses of cellular strategies for achieving high signaling capacity — dynamics, cross-wiring and heterogeneity of cellular states
- Authors:
- Piotr Topolewski, Michał Komorowski
- Academic press:
- Current Opinion in Systems Biology (year: 2021, volume: 27, pages: 100352), Publisher: Elsevier Ltd.
- Status:
- Published
- DOI:
- 10.1016/j.coisb.2021.06.003 – link to the publication