Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The potential role of non-organometallic Ru(II) hydrido complexes as models for cellular redox modulation

2019/33/N/ST4/00700

Keywords:

ruthenium(II) complexes hydride transfer NAD+/NADH catalytic cycle redox modulation reductive stress oxidative stress.

Descriptors:

  • ST4_017:
  • ST4_011:
  • ST4_009:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Marta Jowita Chrzanowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 17 - announced on 2019-03-15

Amount awarded: 69 800 PLN

Project start date (Y-m-d): 2020-02-18

Project end date (Y-m-d): 2021-02-17

Project duration:: 12 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Electronic effects on the mechanism of the NAD+ coenzyme reduction catalysed by non-organometallic ruthenium(II) polypyridyl amine complex in the presence of formate
    Authors:
    Marta Chrzanowska, Anna Katafias, Rudi van Eldik, Jeanet Conradie
    Academic press:
    RSC Advances (rok: 2022, tom: 12, strony: 21191–21202), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/d2ra01890j - link to the publication
  2. Inorganic reaction mechanisms. A personal journey
    Authors:
    Colin D. Hubbard, Debabrata Chatterjee, Maria Oszajca, Justyna Polaczek, Olga Impert, Marta Chrzanowska, Anna Katafias, Ralph Puchta, Rudi van Eldik
    Academic press:
    Dalton Transaction (rok: 2020, tom: 49, strony: 4599-4659), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/c9dt04620h - link to the publication
  3. Tuning the lability of a series of Ru(II) polypyridyl complexes: a comparison of experimental-kinetic and DFT-predicted reaction mechanisms
    Authors:
    Dušan Ćoćić, Marta Chrzanowska, Anna Katafias, Ralph Puchta, Rudi van Eldik
    Academic press:
    Journal of Coordination Chemistry (rok: 2021, tom: 74, strony: 433-443), Wydawca: Taylor&Francis Online
    Status:
    Published
    DOI:
    10.1080/00958972.2021.1874369 - link to the publication
  4. Can a Nonorganometallic Ruthenium(II) Polypyridylamine Complex Catalyze Hydride Transfer? Mechanistic Insight from Solution Kinetics on the Reduction of Coenzyme NAD+ by Formate
    Authors:
    Marta Chrzanowska, Anna Katafias, Rudi van Eldik
    Academic press:
    Inorganic Chemistry (rok: 2020, tom: 59, strony: 14944−14953), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.inorgchem.0c01613 - link to the publication