Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Carbon allotropes as mesenchymal-epithelial transition activators of the phenotype of liver cancer cells via cytokine-dependent pathways

2019/33/N/NZ7/01392

Keywords:

nanomaterials hepatocellular carcinoma metastasis growth factors mesenchymal-epithelial transition

Descriptors:

  • NZ7_016:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Malwina Ewa Sosnowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 17 - announced on 2019-03-15

Amount awarded: 209 909 PLN

Project start date (Y-m-d): 2020-03-16

Project end date (Y-m-d): 2023-03-15

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Graphene oxide nanofilm and chicken embryo extract decrease the invasiveness of HepG2 liver cancer cells
    Authors:
    Sosnowska Malwina, Kutwin Marta, Strojny Barbara, Koczoń Piotr, Szczepaniak Jarosław, Bałaban Jaśmina, Daniluk Karolina, Jaworski Sławomir, Chwalibog Andre, Bielawski Wiesław, Sawosz Ewa
    Academic press:
    Cancer Nanotechnology (rok: 2021, tom: 12, strony: 12055), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1186/s12645-020-00073-5 - link to the publication
  2. Influence of C60 Nanofilm on the Expression of Selected Markers of Mesenchymal–Epithelial Transition in Hepatocellular Carcinoma
    Authors:
    Sosnowska Malwina, Kutwin Marta, Zawadzka Katarzyna, Pruchniewski Michał, Strojny Barbara, Bujalska Zuzanna, Wierzbicki Mateusz, Jaworski Sławomir, Sawosz Ewa
    Academic press:
    Cancers (rok: 2023, tom: 15, strony: 5553), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers15235553 - link to the publication
  3. Diamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells
    Authors:
    Sosnowska Malwina, Kutwin Marta, Strojny Barbara, Wierzbicki Mateusz, Cysewski Dominik, Szczepaniak Jarosław, Ficek Mateusz, Piotr Koczoń, Sławomir Jaworski, Andre Chwalibog, Ewa Sawosz
    Academic press:
    Nanotechnology, Science and Applications (rok: 2021, tom: 14, strony: 115), Wydawca: Dove Medical Press
    Status:
    Published
    DOI:
    10.2147/NSA.S322766 - link to the publication
  4. Polyhydroxylated fullerene C60(OH)40 nanofilms promote the mesenchymal-epithelial transition of human liver cancer cells via the TGF-β1/Smad pathway
    Authors:
    Sosnowska Malwina, Koczoń Piotr, Kutwin Marta, Chwalibog Andre, Sawosz Ewa
    Academic press:
    Journal of Inflammation Research (rok: 2023, tom: 16, strony: 3739-3761), Wydawca: Dove Press
    Status:
    Published
    DOI:
    10.2147/JIR.S415378 - link to the publication

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