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The role of activin A in the regulation of development of preimplantation mammalian embryo

2019/33/B/NZ3/02906

Keywords:

activin mouse rabbit embryo blastocyst cell-cell interactions cell lineage commitment gene deletion CRISPR/Cas9 chimaera embryonic stem cells

Descriptors:

  • NZ3_007:
  • NZ3_008:
  • NZ3_013:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Warszawski, Wydział Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Aneta - Suwińska 

Number of co-investigators in the project: 6

Call: OPUS 17 - announced on 2019-03-15

Amount awarded: 1 995 406 PLN

Project start date (Y-m-d): 2020-02-20

Project end date (Y-m-d): 2025-02-19

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Zygotic activin A is dispensable for the mouse preimplantation embryo development and for the derivation and pluripotency of embryonic stem cells
    Authors:
    Eliza Winek, Lidia Wolińska-Nizioł, Katarzyna Szczepańska, Anna Szpakowska, Olga Gewartowska, Izabela Wysocka, Magdalena Grzesiak, Aneta Suwińska
    Academic press:
    Biology of Reproduction (rok: 2025, tom: 112(1), strony: 31-45), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/biolre/ioae156 - link to the publication
  2. Maternal/zygotic knockout and ddPCR analysis question the role of activin A in preimplantation mouse embryo development
    Authors:
    Eliza Winek, Katarzyna Szczepańska, Lidia Wolińska-Nizioł, Katarzyna Zgódka, Michaela Vaskovicova, David Drutovic, Aneta Suwińska
    Academic press:
    Biology of Reproduction (rok: 2025, tom: -, strony: -), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/biolre/ioaf189 - link to the publication
  3. Chimery z udziałem pluripotentnych komórek macierzystych jako narzędzie w badaniach biomedycznych
    Authors:
    Eliza Winek, Aneta Suwińska
    Academic press:
    Postępy Biochemii (rok: 2021, tom: 67 (4), strony: 395-409)
    Status:
    Published
    DOI:
    10.18388/pb.2021_414 - link to the publication

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