Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The protective role of Klotho protein in the ischemia/reperfusion injury of the cardiomyocytes.

2019/33/N/NZ3/01649

Keywords:

Klotho protein ischemia/reperfusion injury cardioprotection cardiovascular disease cardiac markers

Descriptors:

  • NZ3_001:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Agnieszka Marlena Olejnik 

Number of co-investigators in the project: 3

Call: PRELUDIUM 17 - announced on 2019-03-15

Amount awarded: 209 869 PLN

Project start date (Y-m-d): 2020-02-06

Project end date (Y-m-d): 2025-02-05

Project duration:: 60 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (4)
  1. Klotho Protein Decreases MMP-Mediated Degradation of Contractile Proteins during Ischaemia/Reperfusion Injury to the Cardiomyocytes
    Authors:
    Agnieszka Olejnik, Anna Krzywonos-Zawadzka, Marta Banaszkiewicz, Iwona Bil-Lula
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23 (24), strony: 15450), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms232415450 - link to the publication
  2. Corrigendum to Ameliorating Effect of Klotho Protein on Rat Heart during I/R Injury"
    Authors:
    Agnieszka Olejnik, Anna Krzywonos-Zawadzka, Marta Banaszkiewicz, and Iwona Bil-Lula
    Academic press:
    Oxidative Medicine and Cellular Longevity (rok: 2022, tom: 2022, strony: Article ID 9781367), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2022/9781367 - link to the publication
  3. Corrigendum to Ameliorating Effect of Klotho Protein on Rat Heart during I/R Injury"
    Authors:
    Agnieszka Olejnik, Anna Krzywonos-Zawadzka, Marta Banaszkiewicz, and Iwona Bil-Lula
    Academic press:
    Oxidative Medicine and Cellular Longevity (rok: 2022, tom: 2022, strony: Article ID 9781367), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2022/9781367 - link to the publication
  4. Ameliorating Effect of Klotho Protein on Rat Heart during I/R Injury
    Authors:
    Agnieszka Olejnik, Anna Krzywonos-Zawadzka, Marta Banaszkiewicz, and Iwona Bil-Lula
    Academic press:
    Oxidative Medicine and Cellular Longevity (rok: 2020, tom: 2020, strony: Article ID 6427284), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2020/6427284 - link to the publication
  1. Cardiopreventive effect of Klotho protein on oxidative stress, inflammation and apoptosis during cardiac ischemia/reperfusion injury
    Authors:
    A Olejnik, M Kaminska, A Radajewska, A Krzywonos-Zawadzka, I Bil-Lula
    Conference:
    ESC Preventive Cardiology 2023 - Abstracts, Volume 30, Issue Supplement_1, June 2023, (rok: 2023, tom: Preventive Cardiology 2023, strony: 11404), Wydawca: Oxford University Press
    Data:
    konferencja 13-15.04.2023
    Status:
    Published
    DOI:
    10.1093/eurjpc/zwad125.263 - link to the publication
  2. Cardiopreventive effect of Klotho protein on oxidative stress, inflammation and apoptosis during cardiac ischemia/reperfusion injury
    Authors:
    A Olejnik, M Kaminska, A Radajewska, A Krzywonos-Zawadzka, I Bil-Lula
    Conference:
    ESC Preventive Cardiology 2023 - Abstracts, Volume 30, Issue Supplement_1, June 2023, (rok: 2023, tom: Preventive Cardiology 2023, strony: 11404), Wydawca: Oxford University Press
    Data:
    konferencja 13-15.04.2023
    Status:
    Published
    DOI:
    10.1093/eurjpc/zwad125.263 - link to the publication
  3. Klotho protein supports mechanical function and prevents MMP-mediated injury of heart during ischemia/reperfusion
    Authors:
    Agnieszka Olejnik, Anna Krzywonos-Zawadzka, Marta Kamińska, Iwona Bil-Lula
    Conference:
    EuroThrombosis & EuroVessels 2022 Abstracts (rok: 2022, tom: EuroThrombosis & EuroVessels 2022, strony: ii59 poz.050), Wydawca: Oxford University Press
    Data:
    konferencja 20-22.10.2022
    Status:
    Published
    DOI:
    10.1093/cvr/cvac157.056 - link to the publication
  4. Recombinant Klotho protein contributes to antioxidative protection in ischemia/reperfusion injury of the rat heart
    Authors:
    A. Olejnik, M. Kamińska, A. Radajewska, A. Krzywonos-Zawadzka, I. Bil-Lula
    Conference:
    Cardiovascular diseases and cardiac biomarkers (rok: 2023, tom: WorldLab, EuroMedLab Roma 2023, strony: S485), Wydawca: De Gruyter
    Data:
    konferencja 21-25.05.2023
    Status:
    Published
    DOI:
    10.1515/cclm-2023-7040 - link to the publication