Jakościowa i ilościowa analiza nukleotydów o znaczeniu biologicznym lub terapeutycznym przy użyciu spektrometrii mas

2019/32/T/ST4/00073

Descriptors

  • ST4_002: Metody spektroskopowe i spektrometryczne
  • ST4_005: Chemia analityczna
  • ST4_009: Chemia biologiczna

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Warszawski, Wydział Fizyki

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Dominika Strzelecka

Number of co-investigators in the project: 2

Call

ETIUDA 7 – announced on 2018-12-14

Amount awarded
121 460 PLN
Project start date
2019-10-01
Project end date
2020-09-30
Project duration
12 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

  1. Substrate‐Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism

    Authors:
    Dorota Kubacka, Mateusz Kozarski, Marek R. Baranowski, Radoslaw Wojcik, Joanna Panecka‐Hofman, Dominika Strzelecka, Jerome Basquin, Jacek Jemielity, Joanna Kowalska
    Academic press:
    Pharmaceuticals (year: 2022, volume: 15, pages: 554), Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
    Status:
    Published
    DOI:
    10.3390/ph15050554 – link to the publication
  2. Exploring tryptamine conjugates as pronucleotides of phosphate-modified 7-methylguanine nucleotides targeting cap-dependent translation

    Authors:
    Sebastian Golojuch, Michal Kopcial, Dominika Strzelecka, Renata Kasprzyk, Natalia Baran, Pawel J. Sikorski, Joanna Kowalska, Jacek Jemielity
    Academic press:
    Bioorganic & Medicinal Chemistry (year: 2020, volume: 28, pages: 115523), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bmc.2020.115523 – link to the publication

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